Results 171 to 180 of about 126,119 (267)

Investigations of remibrutinib in models pertinent to multiple sclerosis. [PDF]

Neurotherapeutics
Jain RW, Rayatpour A, Hagen K, Morch MT, Randhawa G, Mobarakabadi M, Zhang X, Li C, Nakhaei-Nejad M, Giuliani F, Cenni B, Xue M, Yong VW.   +12 more
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Yeast as an efficient and eco-friendly bifunctional porogen for biomass-derived nitrogen-doped carbon catalysts in the oxygen reduction reaction

Open Chemistry
Zhang Junjie, Li Gaopan, Fu Yaoming, Peng Xu, Peng Xing, Huang Gangjin, Xia Maosong, Wang Jilong, Li Shixin, Zhu Chuanlong, Chen Yanjun, Luo Dongcheng, Tu Yunbin, Li Xiuyi, Wei Wuguo   +14 more
doaj   +1 more source

A General-Purpose Model Adsorption Isotherm and Whole Isotherm Surface Area Measurement Method. [PDF]

ACS Omega
Manz TA, Delgass WN.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

SIRPγ limits effector differentiation of human CD8 T cells in response to subthreshold TCR-signaling. [PDF]

Immunohorizons
Morse M, Rodriguez X, Delarosa E, Rodriguez S, Shanil J, Sinha S.   +5 more
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Treg-derived IFN-γ supports the differentiation of Th1-Treg in tumor immunity and autoimmunity. [PDF]

Front Immunol
Kuratani A, Okamoto M, Arumsari S, Kobayashi T, Sasai M, Yamamoto M.   +5 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source