Results 61 to 70 of about 135,476 (204)
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye +33 more
wiley +1 more source
Pulmonary macrophages were isolated from naïve mice and stimulated with IFNγ/LPS in presence of I-BET-762 or vehicle for 12h. Expression of MCP-1 (A), KC (B), TNFα (C), IL27p28 (D), and IFNγ (E) were assessed by qPCR. Values are presented as mean ± SEM. *
Ming Yang (109148) +4 more
core +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Stereoselective synthesis of allele-specific BET inhibitors [PDF]
Developing stereoselective synthetic routes that are efficient and cost-effective allows easy access to biologically active molecules. Our previous syntheses of allele-selective bumped inhibitors of the Bromo and Extra-Terminal (BET) domain proteins ...
Testa, Andrea +5 more
core +3 more sources
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
This study reports the production of activated carbon (AC) from chemical activation with sodium hydroxide in pyrolysis temperature of 500 to 600 °C using alternative and renewable material, Buriti petiole.
Cristiane Freitas de Almeida +6 more
doaj +1 more source
Stability of the Bet v 1 cross-reactive allergens Api g 1 and Dau c 1 : a biophysical approach [PDF]
The allergen Bet v 1 is known as the primary sensitizer for birch pollen-related food allergy and is responsible for IgE cross-reactivity to pathogenesis-related 10 (PR-10) proteins from, in particular, fruits from the Rosaceae and vegetables from the ...
Bollen, M.A.
core
Recombinant MCP-1 administration overcomes I-BET-762-mediated suppression of AHR and inflammation.
Mice were administered IFNγ/LPS/rMCP-1 i.t at 0h. Some groups were treated with I-BET-762 i.v 1h before and 4h after IFNγ/LPS/rMCP-1 exposure. Endpoints were assessed at 12h.
Ming Yang (109148) +4 more
core +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
I-BET-762 treatment suppresses AHR and inflammatory cell infiltration in RSV-induced exacerbation.
BALB/c mice were sensitised i.p with OVA or PBS plus alum on day 0 and exposed to OVA aerosol on days 13–16. Some mice were inoculated with RSV on day 19 and treated with I-BET-762 or vehicle (hydroxyl-β cyclodextrin) i.v twice on day 23.
Ming Yang (109148) +4 more
core +1 more source

