Results 51 to 60 of about 135,476 (204)
IMMUNOTHERAPEUTIC ACTION OF T-BET GENE MODIFIED DENDRITIC CELLS [PDF]
, 2013 T-bet is a Type-1 transcription factor that regulates the development of Type-1 T cell and Type-1 anti-tumor immunity. T-bet expression in Dendritic Cells (DC) is required for the ability of these antigen-presenting cells (APC) to prime Type-1-polarized ...
Chen, Lu
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess +5 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu +8 more
wiley +1 more source
I-BET-762 treatment suppresses lung inflammatory cytokines after IFNγ/LPS stimulation.
, 2016 Effect of I-BET-762 administration on MCP-1, KC, TNFα, IL-27p28 and IFNγ (A) mRNA levels and (B) protein levels in whole lung tissue. Representative of three independent experiments, n = 6–8 mice per group, presented as mean ± SEM.
Ming Yang (109148) +4 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak +9 more
wiley +1 more source
SSM: Population HealthBackground: Breast cancer is the leading cause of cancer death in Israeli women. Previous studies found socioeconomic status and other risk factors impact breast cancer outcomes.
Ronit Pinchas-Mizrachi +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
Bet-hedging region in temporally varying environments.
, 2019 Optimal strategy α* as a function of growth rates and for range expansions in temporally varying environments under the limits of environmental change rate (A) k → 0, see Eq (7), and (B) k → ∞. In all panels, lines delimit the bet-hedging region 0 ≤ α*
Simone Pigolotti (160209) +2 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling +2 more
wiley +1 more source
I-BET-762 treatment suppresses AHR and inflammatory cells after IFNγ/LPS stimulation.
, 2016 Mice were administered IFNγ/LPS i.t at 0h. Some mice were treated with I-BET-762 or vehicle (hydroxyl-β cyclodextrin) i.v 1h before and 4h after IFNγ/LPS exposure. Endpoints were assessed at 12h.
Ming Yang (109148) +4 more
core +1 more source