Results 131 to 140 of about 245,414 (303)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

To Bet or Not to Bet on T-bet As a Therapeutic Target in Emphysema?

open access: yesAmerican Journal of Respiratory Cell and Molecular Biology, 2019
Xiaoyun Wang   +2 more
openaire   +2 more sources

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Fundamentos da Dança I

open access: yes, 2017
Este material de apoio tem como objetivo expandir seus conhecimentos no campo da Arte, percorrendo o caminho da fundamentação de termos, de conceitos e períodos artísticos.
Bet, Karine Zenaide
core  

BET-HEDGING IN HETEROCARPIC GRINDELIA CILIATA (ASTERACEAE) [PDF]

open access: yes, 2017
A challenge for all living organisms is to offset the fitness associated risks of environmental uncertainty. Bet-hedging strategies are adaptive in unpredictable environments and are documented in a wide range of taxa spanning all kingdoms (Simons 2011 ...
Kistenmacher, Michael
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Bet- und Lehrhaus Petriplatz Berlin

open access: yes
BET- UND LEHRHAUS PETRIPLATZ BERLIN Bet- und Lehrhaus Petriplatz Berlin (Rights reserved) Ausgabe [1] Ausschreibung (Rights ...

core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

T-bet-deficient X RORγt mutant mice and IL-12p40-deficient mice show altered patterns of Th1 and Th17 markers.

open access: yes
Lymphocytes isolated from the FRT and ILN were stimulated with PMA and ionomycin with Brefeldin A before staining for flow cytometry. Results are gated on CD4+ CD44hi cells.
Kevin D. Fong (17721439)   +5 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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