Results 121 to 130 of about 135,476 (204)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Linking obesity with type 2 diabetes: the role of T-bet
, 2014 Jibran A Wali,1,2 Helen E Thomas,1,2 Andrew PR Sutherland1 1Immunology and Diabetes Unit, St Vincent's Institute, 2Department of Medicine, St Vincent's Hospital, University of Melbourne, Fitzroy, Victoria, Australia Abstract: Obesity is a major ...
APR, Wali JA, Sutherl, Thomas HE
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Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Regulation of T-bet Translation in the YT Cell Line by Secondary Structures of the 5’ and 3’UTR
, 2010 自然殺手細胞 (NK cell) 是一種存在於先天免疫系統 (innate immune system) 中具有毒殺細胞能力的淋巴球，它們能夠抵禦癌細胞以及被病毒感染的細胞。目前所知NK 細胞所表現的細胞激素除了TNF-α、GM-CSF 之外，也會分別表現不同的細胞激素而分類為 type II、type 0 及 type I 三個亞群，它們表現的細胞激素分別為 IL13+ / IL5+、IL13+ / IFN-γ+、IFN-γ++。另一方面，若以細胞表面分子 CD56 來定義 NK 細胞發育的成熟度 ...
賴怡安, Lai, I-An
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Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Inverse Single-Strand RACE: An Adapter-Independent Method of 5′RACE
BioTechniques, 1999 Yoram Eyal +3 more
doaj +1 more source
Lymphocytes isolated from the FRT and ILN were stimulated with PMA and ionomycin with Brefeldin A before staining for flow cytometry. Results are gated on CD4+ CD44hi cells.
Kevin D. Fong (17721439) +5 more
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
, 1970 beatPast tense of _to beat_ (at a game, or race, in contest). "Our team bet Collegiate at hockey." "One more hand [of cards] and we'd have you bet!"Past tense of to beatJH 1/70Used I and SupNot usedNot used'to beat' is ...
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