Results 131 to 140 of about 263,197 (302)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Regulation of T-bet Translation in the YT Cell Line by Secondary Structures of the 5’ and 3’UTR

open access: yes, 2010
自然殺手細胞 (NK cell) 是一種存在於先天免疫系統 (innate immune system) 中具有毒殺細胞能力的淋巴球,它們能夠抵禦癌細胞以及被病毒感染的細胞。目前所知NK 細胞所表現的細胞激素除了TNF-α、GM-CSF 之外,也會分別表現不同的細胞激素而分類為 type II、type 0 及 type I 三個亞群,它們表現的細胞激素分別為 IL13+ / IL5+、IL13+ / IFN-γ+、IFN-γ++。另一方面,若以細胞表面分子 CD56 來定義 NK 細胞發育的成熟度 ...
賴怡安, Lai, I-An
core  

Herbivory Dependent Bet-Hedging Model

open access: yes, 2016
Herbivory Dependent Bet-Hedging ...
Michael Kistenmacher (3198609)   +1 more
core   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Inverse Single-Strand RACE: An Adapter-Independent Method of 5′RACE

open access: yesBioTechniques, 1999
Yoram Eyal   +3 more
doaj   +1 more source

To Bet or Not to Bet on T-bet As a Therapeutic Target in Emphysema?

open access: yesAmerican Journal of Respiratory Cell and Molecular Biology, 2019
Xiaoyun Wang   +2 more
openaire   +2 more sources

Betting on Scams

open access: yesSocial Epistemology
Scams of all sorts are responsible for huge financial and psychological harms. Up to now, however, there’s been no philosophical investigation of how they work. I argue that while the success of some scams is easily explained, others are puzzling. Especially in light of the growing evidence that we have well-designed epistemic vigilance systems that ...
openaire   +1 more source

T-bet-deficient X RORγt mutant mice and IL-12p40-deficient mice show altered patterns of Th1 and Th17 markers.

open access: yes
Lymphocytes isolated from the FRT and ILN were stimulated with PMA and ionomycin with Brefeldin A before staining for flow cytometry. Results are gated on CD4+ CD44hi cells.
Kevin D. Fong (17721439)   +5 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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