Results 111 to 120 of about 215,969 (313)

Nghiên cứu ảnh hưởng của các điều kiện tổng hợp lên đặc tính sản phẩm carbon nano ống biến tính bằng nitơ

open access: yesTạp chí Khoa học và Công nghệ
Ở nghiên cứu này, nhóm tác giả đã tiến hành khảo sát sự thay đổi về hiệu suất và các đặc tính của N-CNTs như hình thái bề mặt, giá trị BET, độ ổn định oxy hóa theo nhiệt độ tổng hợp và thể tích NH4OH.
Lê Đức Ngưu   +2 more
doaj  

Bet-hedging data set

open access: yes, 2015
Data set documenting that Nothobranchius furzeri embryos (of known parentage incubated under common garden laboratory conditions: 25 degrees Celsius, in the dark, on moist peat moss) are capable of following either the diapause or direct-developing ...
Kevin Lee (96151)   +5 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Recherches récentes en pays de Thelle

open access: yes, 1977
Bet Philippe. Recherches récentes en pays de Thelle. In: Cahiers archéologiques de Picardie, n°4, 1977. pp.
Bet, Philippe
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Bet- und Lehrhaus Petriplatz Berlin

open access: yes
BET- UND LEHRHAUS PETRIPLATZ BERLIN Bet- und Lehrhaus Petriplatz Berlin (Rights reserved) Ausgabe [1] Ausschreibung (Rights ...

core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

T-bet-deficient X RORγt mutant mice and IL-12p40-deficient mice show altered patterns of Th1 and Th17 markers.

open access: yes
Lymphocytes isolated from the FRT and ILN were stimulated with PMA and ionomycin with Brefeldin A before staining for flow cytometry. Results are gated on CD4+ CD44hi cells.
Kevin D. Fong (17721439)   +5 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

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