Results 81 to 90 of about 245,988 (303)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The viral etiology of tomato yellow leaf curl disease - a review
Plant Protection Science, 2009 Tomato yellow leaf curl disease (TYLCD) is one of the most devastating plant diseases in the world. As a result of its continuing rapid spread, it now afflicts more than 30 tomato growing countries in the Mediterranean basin, southern Asia, Africa, and ...
Efrat Glick, Yael Levy, Yedidya Gafni
doaj +1 more source
BET-Inhibitors Disrupt Rad21-Dependent Conformational Control of KSHV Latency.
, 2017 Kaposi's Sarcoma-associated Herpesvirus (KSHV) establishes stable latent infection in B-lymphocytes and pleural effusion lymphomas (PELs). During latency, the viral genome persists as an epigenetically constrained episome with restricted gene expression ...
Alessandra De Leo +11 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Comparative study between supported bimetallic catalysts for nitrate remediation in water
Open Chemistry, 2023 Rachini Mouhamad +14 more
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Pengaruh Temperatur dan Waktu Kabonisasi pada Sintesis Porous Carbon Berbahan Dasar Molase
Jurnal Kimia Sains dan Aplikasi, 2009 Telah dilakukan penelitian tentang pengaruh temperatur dan waktu karbonisasi pada sintesis porous carbon berbahan dasar molase. Molase merupakan hasil samping pabrik gula yang memiliki kandungan sukrosa yang sudah tidak dapat dikristalkan lagi ...
Asti Ayuk Putri Pertiwi +2 more
doaj +1 more source
Luck or Skill? An Examination of the Ehrlich - Simon Bet [PDF]
In 1980, Paul Ehrlich and Julian Simon placed a famous bet on whether the prices of a bundle of natural resources would rise or fall over the ensuing decade. Simon won the bet as the real price of the bundle fell significantly, and the result of this bet
Kevin Golembiewski +2 more
core
, 2020 This release is not entirely backwards compatible, but maintains backwards compatibility wherever possible. It comprises a significant refactoring of the entire codebase. The main change is the addition of density-based methods.
Scott Walsh +6 more
core +1 more source