Results 131 to 140 of about 125,959 (267)

M¹ündlich - S(t)imulation of competency-oriented learning in physiology. [PDF]

BMC Med Educ
Eiring L, Benson S, Fandrey J, Prost-Fingerle K, Winning S.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Remote-Based Brain Endurance Training Enhances Bench Press, Preacher Curl, and Jump Squat Performance in Recreational Athletes. [PDF]

Eur J Sport Sci
Rautu A, Woods J, Mortimer H, Dallaway N, Ring C.   +4 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Prenatal Methyl Nutrient Availability Shapes Mesolimbic Dopaminergic Circuitry and Systemic Inflammation in Wistar Rat Offspring of Both Sexes. [PDF]

J Neurochem
Di Pierdomenico C, Cook WJJ, Dong J, Shelp GV, Poole EM, Burns SE, Cho CE.   +6 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Pyrolysis of Camellia oleifera Shell at Intermediate Temperatures, and Prediction of Bio-oil Component Levels by Mathematical Modeling

BioResources
Camellia oleifera shell was pyrolysed at 300 to 750 °C to investigate biochar and bio-oil yields under different conditions, and the relationships between pyrolysis temperature and the product yields were established.
Rongqu Bei, Wenrui Xie, Xuefei Gan, Yuefang Chen, Zhengbin He   +4 more
doaj  

Targeting BRD2 and BRD4 inhibit the growth of KSHV-infected immortalized endothelial cells through suppression of LANA translation. [PDF]

PLoS Pathog
Chen J, Fan J, Qin M, Lin Z, Mu S, Dai L, Qin Z.   +6 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

How toothed whales divide up the world: phylogeny and ecology shape life-history strategies of odontocetes. [PDF]

BMC Ecol Evol
Ferguson SH, Feyrer LJ, de Greef E, Higdon JW.   +3 more
europepmc   +1 more source