Results 241 to 250 of about 187,919 (323)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Comparative evaluation of beta-blockers with or without statins in the treatment of essential hypertension at a tertiary health care setup

, 2015
Shalu Bawa, Shakti Dutta, Hitender Kumar, Mirza Beg, Amit Varma, Mohammad Anjoom   +5 more
openalex   +2 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Effectiveness of Beta-Blockers in Reducing Mortality and Recurrence After Myocardial Infarction: A Systematic Review of Contemporary and Foundational Evidence. [PDF]

Cureus
Popraya AM, Ibrahim M, Anthony N, Anmol S, Ahmed F, Kamran B.   +5 more
europepmc   +1 more source

EFFECT OF BETA-BLOCKERS ON BLOOD PRESSURE, PERIOPERATIVE COMPLICATIONS AND HOSPITAL STAY DURATION IN PATIENTS WITH INTERMEDIATE RISK OF CARDIOVASCULAR COMPLICATIONS AFTER ROUTINE CHOLECYSTECTOMY: AN OPEN COMPARATIVE RANDOMIZED STUDY

, 2010
О. Л. Барбараш, Р. В. Репникова, Т. В. Шофорусь, О. И. Голофаева   +3 more
openalex   +2 more sources

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Beta-blockers in patients with heart failure with reduced ejection fraction and concomitant chronic obstructive pulmonary disease: Cardiovascular and respiratory outcomes. [PDF]

Eur J Heart Fail
Beer BN, Benson L, Basile C, Schrage B, Becher PM, Blankenberg S, Kirchhof P, Szabó-Söderberg B, Metra M, Lindberg A, Imbalzano E, Rosano GMC, Karlström P, Mol PGM, Scorza R, Lund LH, Lindberg F, Savarese G.   +17 more
europepmc   +1 more source

Traumatic Microhemorrhages Are Not Synonymous With Axonal Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diffuse axonal injury (DAI) is caused by acceleration‐deceleration forces during trauma that shear white matter tracts. Susceptibility‐weighted MRI (SWI) identifies microbleeds that are considered the radiologic hallmark of DAI and are used in clinical prognostication.
Karinn Sytsma, Rhonda Mittenzwei, Heather Maioli, Amanda Kirkland, C. Dirk Keene, Ramon Diaz‐Arrastia, Christine Mac Donald, Chiara Maffei, Brian L. Edlow, Amber L. Nolan   +9 more
wiley   +1 more source

ASO Author Reflections: The Role of Beta-Blockers in Gastric Cancer-A Pathway to Personalized Therapy? [PDF]

Ann Surg Oncol
Crnovrsanin N, Zumsande S, Rompen IF, Schiefer S, Zimmer S, Hu W, Arnscheidt J, Brinkmann F, Longerich T, Haag GM, Schmidt T, Al-Saeedi M, Sisic L, Nienhüser H.   +13 more
europepmc   +1 more source

Exploring Patients’ Profiles Associated With the Resolution of Acute Calcium Pyrophosphate Arthritis Treated With Colchicine and Prednisone: Post Hoc Analysis of a Randomized Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source