Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley +12 more
wiley +1 more source
This work demonstrates the successful integration of a phenanthroline‐based 2D COF with MnI catalytic sites into a catholyte‐free membrane‐electrode‐assembly cell for CO2 electroreduction. The crystalline COF actively suppresses Mn⁰–Mn⁰ dimerization, achieving a turnover frequency of 617 h⁻¹ at 2.8 V (full‐cell potential), and enabling stable operation.
Laura Spies +8 more
wiley +1 more source
GPs' views of prescribing beta- blockers for people with anxiety disorders: a qualitative study. [PDF]
Archer C +4 more
europepmc +1 more source
Reconfigurable Three‐Dimensional Superconducting Nanoarchitectures
3D superconducting nanostructures offer new possibilities for emergent physical phenomena. However, fabricating complex geometries remains challenging. Here 3D nanoprinting of complex 3D superconducting nanoarchitectures is established. As well as propagating superconducting vortices in 3D, anisotropic superconducting properties with geometric ...
Elina Zhakina +11 more
wiley +1 more source
Risk of progression in intermediate age-related macular degeneration among patients using systemic beta-blockers. [PDF]
Hogan B +12 more
europepmc +1 more source
The Effects of Beta-Blockers on Leukocytes and the Leukocyte Subpopulation in Heart Failure Patients. [PDF]
Farcaş AD +5 more
europepmc +1 more source
Continuation vs Withdrawal of Beta-Blockers and Outcomes After Myocardial Infarction With Preserved Left Ventricular Function. [PDF]
Chiu MH +9 more
europepmc +1 more source
Beta-blockers in post-myocardial infarction with preserved ejection fraction: systematic review and meta-analysis. [PDF]
Gomes RAF +3 more
europepmc +1 more source
Beta-blockers prolong response to androgen deprivation therapy in prostate cancer through modulation of the neuro-immuno-oncology axis. [PDF]
Thulin MH +14 more
europepmc +1 more source

