Engineering of High‐Yield Recombinant Adeno‐Associated Virus Producer Plasmids
Graphical Abstract and Lay Summary Recombinant adeno‐associated viruses (AAV) are important in gene therapy but their production may be impaired by non‐optimized gene design. In this study, the authors demonstrate that production was best when the AAV replicase gene was in a wild‐type configuration while the complexity of other genetic elements could ...
Marco T. Radukic +10 more
wiley +1 more source
Molecular Characterization of KPC-2 and CMY AmpC Beta Lactamases in Ceftazidime-Avibactam Resistant Klebsiella pneumoniae in a Tertiary Care Hospital. [PDF]
Haseeb U +6 more
europepmc +1 more source
Genetic Diversity of Escherichia coli Coharboring mcr-1 and Extended Spectrum Beta-Lactamases from Poultry. [PDF]
Jamil A +4 more
europepmc +1 more source
Prevalence and Characterization of Cephalosporin Resistance in Nonpathogenic Escherichia coli from Food-Producing Animals Slaughtered in Poland [PDF]
Aarestrup, Frank Møller +3 more
core +1 more source
We demonstrate that bacterial outer membrane vesicles (OMVs) can enhance antibiotic delivery into Gram‐negative bacteria by bypassing porin‐dependent uptake. Encapsulation of imipenem in OMVs significantly increased its effectiveness against multidrug‐resistant clinical isolates, highlighting OMVs as a promising platform for overcoming permeability ...
Meishan Wu +3 more
wiley +1 more source
Extended-spectrum beta-lactamases: definition, history, an update on their genetic environment and detection methods. [PDF]
Yassara S +4 more
europepmc +1 more source
Cefixime and cefixime-clavulanate for screening and confirmation of extended-spectrum beta-lactamases in Escherichia coli. [PDF]
Al-Tamimi M +5 more
europepmc +1 more source

