Results 191 to 200 of about 1,352,947 (309)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Numerical Investigation of Beta Ratio and Reynolds Number Effect on Coefficient of Discharge of Venturimeter

, 2020
Abdul Razak Kaladgi, Arafat Mukhtar, Asif Afzal, Mohammed Kareemullah, M. K. Ramis   +4 more
openalex   +1 more source

Diminishing returns of disease-modifying treatment in older participants of multiple sclerosis clinical trials. [PDF]

Mult Scler
Strijbis E, Mostert J, D'Haeseleer M, Moral E, Brieva Ruiz L, Comtois J, Killestein J, Repovic P, McPherson T, Cutter G, Koch M.   +10 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Major Depression in Children with β-Thalassemia Major is Strongly Associated with the Number of Blood Transfusions, Iron Overload and Increased Levels of Interleukin-1β

, 2019
Hussein Kadhem Al‐Hakeim, Asawer Hassan Najm, Arafat Hussein Al-Aldujaili, Michaël Maes   +3 more
openalex   +2 more sources

New, Shorter Small-Sample Intervals for Vaccine Efficacy. [PDF]

Pharm Stat
Gasparini M, Trani VD, Ratta M.
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Evaluating use of disease-modifying therapies for multiple sclerosis using claims data. [PDF]

Front Health Serv
Wang X, Zhao FL, Newby D, Li S.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Amyloid beta from axons and dendrites reduces local spine number and plasticity

, 2009
Wei Wei, Louis N. Nguyen, Helmut W. Kessels, H Hagiwara, Sangram S. Sisodia, Roberto Malinow   +5 more
openalex   +2 more sources