Results 161 to 170 of about 53,686 (285)
British Journal of Haematology, Volume 208, Issue 1, Page 348-352, January 2026.In this post hoc analysis of the phase 2 BEYOND trial, the majority of patients with non‐transfusion‐dependent β‐thalassaemia achieved clinically meaningful haemoglobin levels ≥10.0 g/dL and increases from baseline ≥1.0 g/dL, thresholds associated with reduced risk of morbidity and mortality and recommended as an indication and target for treatment by ...
Khaled M. Musallam +11 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 1, January 2026.ABSTRACT Maternal cell contamination (MCC) in fetal specimens poses a major risk for misdiagnosis in prenatal genetic testing. Standard variable number tandem repeat (VNTR) analysis of the thyroid peroxidase (TPO) gene intron 10 is informative for MCC detection but traditionally requires DNA extraction, limiting its use in resource‐limited laboratories.
Phongsathorn Wichian +5 more
wiley +1 more source
Iron‐related intercellular communication in the liver: Main players and mechanisms
European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.Iron exchange between liver cell types is vital for organism health, yet its mechanisms remain poorly understood. In this review, we address intercellular communication governing hepatic iron regulation across different liver diseases. We summarize recent insights into how hepatocytes, macrophages, endothelial and stellate cells coordinate iron storage,
Óscar Fonseca +4 more
wiley +1 more source
Journal of Tehran University Heart Center, 2015 Background: Heart disease is the main cause of mortality and morbidity in patients with beta thalassemia, rendering its early diagnosis vital. We studied and compared echocardiographic findings in patients with beta thalassemia major, patients with beta ...
Noormohammad Noori +5 more
doaj
Detection of Rare Thalassemia Variants Using Accurate Circular Consensus Long‐Read Sequencing
Human Mutation, Volume 2026, Issue 1, 2026.Objective The aim of this study is to evaluate the efficacy of accurate circular consensus long‐read sequencing in the detection of rare thalassemia. Methods Conventional molecular analysis on globin genes has limitations because of the broad spectrum of genetic variants, complex genetics, and genotype–phenotype correlation. Accurate circular consensus
Xiaoqiang Zhou +10 more
wiley +1 more source
Renal tubular dysfunction with nephrocalcinosis in a patient with beta thalassemia minor
Saudi Journal of Kidney Diseases and Transplantation, 2008 Thalassemia is a hereditary anemia resulting from defect in hemoglobin production. Beta thalassemia is due to impaired production of beta globin chains, leading to a relative excess of alpha globin chains.
Prabahar Murugesan +4 more
doaj
Beta Thalassemia Carriers detection empowered federated Learning [PDF]
, 2023 Muhammad Shoaib Farooq, Hafiz Ali Younas
openalex +1 more source
International Research Journal of Modernization in Engineering Technology and Science, 2023 openaire +1 more source