Results 171 to 180 of about 2,268,451 (316)

Beta-blocker therapy after myocardial infarction: an umbrella review. [PDF]

EClinicalMedicine
Cataldo-Miranda P, Cao PK, Koh HJW, Gasevic D, Chodapuneedi S, Eliakundu AL, Romero L, Stub D, Zoungas S, Kaye DM, Talic S.   +10 more
europepmc   +1 more source

A Physiological Role for Amyloid Beta Protein: Enhancement of Learning and Memory

, 2008
Amyloid beta protein (A[beta]) is well recognized as having a significant role in the pathogenesis of Alzheimer's disease (AD). The reason for the presence of A[beta] and its physiological role in non-disease states is not clear.
John Morley, Steven N. Johnson, Lin Xu, William Banks, Kelvin A. Yamada, Susan Farr   +5 more
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Likelihood of aggressive PK/PD target attainment of continuous-infusion beta-lactams during the first week of treatment of febrile neutropenia: findings from a 1-year prospective, monocentric study in onco-haematological patients. [PDF]

J Antimicrob Chemother
Cojutti PG, Toschi A, Pasquini Z, Paolini S, Maffini E, Bonifazi F, Zinzani PL, Giannella M, Viale P, Pea F.   +9 more
europepmc   +1 more source

Beta Regression in R

The class of beta regression models is commonly used by practitioners to model variables that assume values in the standard unit interval (0, 1). It is based on the assumption that the dependent variable is beta-distributed and that its mean is related ...
Achim Zeileis, Francisco Cribari-Neto
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Beta bursts spatiotemporal profiles and their links to hemodynamic responses during movement and rest. [PDF]

Imaging Neurosci (Camb)
Long S, Boudrias MH, Mitsis GD.
europepmc   +1 more source

Announcement of three new campus chapters of the Phi Beta Kappa Society

, 2012
Advertisement in The Chronicle of Higher Education, v.LIX, no.2, September 7, 2012, p ...
Phi Beta Kappa Society
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Rewiring Recovery: Cognitive and Motor Gains Through Personalized Neurofeedback After Tumor Resection-A Case Series from Neurorehabilitation Practice. [PDF]

Appl Psychophysiol Biofeedback
Lagravinese G, Nicolardi V, Aresta S, Guglielmo M, Tagliente S, Montenegro F, Battista P, Parsons B, De Trane S.   +8 more
europepmc   +1 more source