Results 211 to 220 of about 2,548,724 (247)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The lncRNA PHAROH augments MYC mRNA levels in insulin-producing cells by counteracting TIA1-induced MYC silencing. [PDF]

Sci Rep
Zhao T, Welsh N.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Hydroxyl‑Mediated SO₂ Promotion Enables Efficient NO_x Reduction by CO over IrIn/Beta under Oxygen‑Rich Conditions. [PDF]

Nat Commun
Yuan Y, Wang Y, Xu W, Wang Y, Yang Y, Ma X, Zhu T.   +6 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Salience network hub dysfunction is associated with cognitive impairment in self-limited epilepsy with centrotemporal spikes: An OPM-MEG study. [PDF]

Epilepsia Open
Yang C, Wu G, An N, Jiang T, Wang Y, Zhao W, Cao W, Wang X, Jiang H, Yuan Z.   +9 more
europepmc   +1 more source

Linking Embodiment, Simulator Sickness, and EEG Activity During XR-BCI Use: A Single-Participant Case Study. [PDF]

Life (Basel)
Tomás DJ, Pais-Vieira M, Pais-Vieira C.
europepmc   +1 more source

Beta-Blocker Use and Self-Reported Sleep Changes Among Medical Students in Jordan: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Alzoubi M, Al Safadi W, Sorour S, Ammori R, Ahmad A, Dawud Y, Shalash F, Mohammad M, Mohammad MT.   +8 more
europepmc   +1 more source