Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae +53 more
wiley +1 more source
Cross-Talk Between Signaling and Transcriptional Networks Regulating Thermogenesis-Insights into Canonical and Non-Canonical Regulatory Pathways. [PDF]
Simka-Lampa K.
europepmc +1 more source
ABSTRACT Amniotic fluid embolism (AFE) is a devastating and unpredictable obstetric emergency typically characterized by sudden cardiopulmonary collapse and coagulopathy during or shortly after delivery. It is triggered by an anaphylactoid‐histamine‐mediated systemic response, evidently with no available confirmatory tests in living patients.
Aniceth Muchunguzi +4 more
wiley +1 more source
The slow delayed rectifier K<sup>+</sup> current is differently regulated under baseline conditions and following β-adrenergic stimulation in canine ventricular cardiomyocytes. [PDF]
Horváth B +7 more
europepmc +1 more source
Ximenia americana L. From Popular Use to Anti‐Inflammatory Activities: A Comprehensive Review
ABSTRACT Ximenia americana (L.), known as “yellow plum,” “sea lemon,” or “Brazilian plum,” is a tropical/subtropical plant widely used in traditional medicine. Its roots, leaves, flowers, stem, and fruits are traditionally employed to treat various inflammatory disorders.
Bruno Anderson F. Silva +9 more
wiley +1 more source
Investigation of the mechanism of Yijing Decoction in the treatment of premature ovarian insufficiency: A network pharmacology study. [PDF]
Xu Y +6 more
europepmc +1 more source
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley +1 more source
Prostaglandin analog therapy challenges and innovation in glaucoma therapeutics. [PDF]
Nath M +4 more
europepmc +1 more source
Cardioprotective Mechanisms of Beta-Blockers in Myocardial Ischemia and Reperfusion: From Molecular Targets to Clinical Implications. [PDF]
Nasoufidou A +10 more
europepmc +1 more source
Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source

