Results 181 to 190 of about 189,690 (343)

The Beta-blocker chronicle: From past principles to present practice - Implications for the Indian subcontinent. [PDF]

Indian Heart J
Ray S, Saboo B, Roy D, Prasad Sinha D, Kahali D, Kanti Das M, Tyagi S, Tewari S, Kumar Chopra H, Pal J, Yadav R.   +10 more
europepmc   +1 more source

Adherence to Beta-Blockers and Long-Term Risk of Heart Failure and Mortality After a Myocardial Infarction [PDF]

, 2020
Liyew Desta, Masih Khedri, Tomas Jernberg, Pontus Andell, Moman A. Mohammad, Claes Hofman‐Bang, David Erlinge, Jonas Spaak, Hans Persson   +8 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Long-Term Outcomes: Beta-Blocker Use and Permanent Pacing in Patients With Heart Failure Preserved Ejection Fraction. [PDF]

JACC Adv
Gabriels JK, Coleman K, Fishbein J, Cunn G, Bekiaridou A, Varrias D, Sharma N, Mokhtari M, George R, Brennan C, Gandomi A, Vullaganti S, Epstein LM, Mountantonakis SE.   +13 more
europepmc   +1 more source

Beta-blockers in patients with refractory ascites: To treat or not to treat. That is the question? But, what is the answer? [PDF]

, 2012
Mónica Guevara, Roberto J. Groszmann, Yasuko Iwakiri, Tamar H. Taddei   +3 more
openalex   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Beta-blocker use and survival outcomes in colorectal cancer patients: A systematic review and meta-analysis. [PDF]

J Int Med Res
Li R, Chen J, Chen Y, Jin K, Chen Y, Deng C, Liu X, Li Y.   +7 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Beta-Blocker Therapy After Myocardial Infarction. [PDF]

JACC Adv
Cataldo Miranda P, Gasevic D, Trin C, Stub D, Zoungas S, Kaye DM, Orman Z, Eliakundu AL, Talic S.   +8 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source