Results 181 to 190 of about 8,645,876 (363)

Simulation modeling: an illustrative method to estimate drug clinical and economic effectiveness (retrospective meta-analysis of anti-asthmatic therapy in children in a hospital setting)

Сеченовский вестник, 2017
The article presents an assessment of the clinical, economic and clinical-economic components of the basic anti-asthmatic therapy regimens in children in hospital setting.
O. V. Zhukova
doaj  

Some utilization of the Beta distribution in statistics

, 2013
Luigi Greco
openalex   +1 more source

A note on the estimate of the beta distribution [PDF]

, 2012
Dawei Lu, Jinghai Feng, Xingzhi Liang
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

- Beta Distribution [PDF]

, 2016
openaire   +1 more source

Constructions for a bivariate beta distribution [PDF]

, 2014
I. Olkin, T. Trikalinos
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

On the Comparison of Particle Swarm Optimization Algorithm Performance using Beta Probability Distribution [PDF]

, 2014
ByungSeok Lee, Joon Hwa Lee, Moon-Beom Heo   +2 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A Practical Framework to Design Immunization Studies Based on the Beta Distribution. [PDF]

Stat Med
Embacher S, Berghold A, Maertens K, Herzog SA.   +3 more
europepmc   +1 more source