We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Assessing the contributions of site and species to plant beta diversity in alpine grassland ecosystems. [PDF]
Li J, Pang XP, Guo ZG.
europepmc +1 more source
Heterogeneous Habitats in Taiga Forests with Different Important Values of Constructive Species Changes Bacterial Beta Diversity. [PDF]
Zhou T, Wu S, Pan H, Lu X, Du J, Yang L.
europepmc +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Ground-lying deadwood volume promotes soil beta diversity but not alpha diversity in European temperate forests. [PDF]
Rousseau M +7 more
europepmc +1 more source
Regional climate contributes more than geographic distance to beta diversity of copepods (Crustacea Copepoda) between caves of Italy. [PDF]
Galmarini E +8 more
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Benchmarking beta-diversity measures and transfer functions for sedimentary ancient DNA. [PDF]
Cordier T, Keck F, Lanzén A.
europepmc +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
Modelling the alpha and beta diversity of copepods across tropical and subtropical Atlantic ecoregions. [PDF]
Martínez-Leiva L +5 more
europepmc +1 more source

