Results 211 to 220 of about 3,133,166 (336)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Temporal Beta Diversity of Bacteria in Streams: Network Position Matters But Differently for Bacterioplankton and Biofilm Communities. [PDF]

Microb Ecol
Huttunen KL, Malazarte J, Jyväsjärvi J, Lehosmaa K, Muotka T.   +4 more
europepmc   +1 more source

Flex Meta-Storms elucidates the microbiome local beta-diversity under specific phenotypes. [PDF]

Bioinformatics, 2023
Zhang M, Zhang W, Chen Y, Zhao J, Wu S, Su X.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Divergent alpha and beta diversity trends of soil nematode fauna along gradients of environmental change in the Carpathian Ecoregion. [PDF]

Commun Biol
Archidona-Yuste A, Ciobanu M, Kardol P, Eisenhauer N.   +3 more
europepmc   +1 more source

Nestedness and beta diversity of gastrointestinal helminth communities in common warthogs, Phacochoerus africanus (Suidae), at 2 localities in South Africa. [PDF]

Parasitology, 2023
Junker K, Horak IG, Boomker J, Krasnov BR.   +3 more
europepmc   +1 more source

A meta‐analysis of nestedness and turnover components of beta diversity across organisms and ecosystems

, 2018
J. Soininen, J. Heino, Jianjun Wang
semanticscholar   +1 more source

Drying determines the temporal dynamics of stream invertebrate structural and functional beta diversity

, 2020
J. Crabot, J. Heino, B. Launay, T. Datry
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Distinct spatiotemporal patterns between fungal alpha and beta diversity of soil-plant continuum in rubber tree. [PDF]

Microbiol Spectr
Wei Y, Wu Z, Lan G.
europepmc   +1 more source