Results 191 to 200 of about 1,095,525 (267)

The long-term neuroprotective effect of MIND and Mediterranean diet on patients with Alzheimer's disease. [PDF]

Sci Rep
Liu X, Yang B, Liu Q, Gao M, Luo M.
europepmc   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Auditory sensory processing induces cortical and thalamic event-related desynchronization in the mouse. [PDF]

PLoS One
McGill SH, Xin Q, Yadav T, Zhao CW, Paszkowski P, Darby F, Guha M, Nguyen T, Jin DS, Nir Y, Liu J, Sieu LA, Blumenfeld H.   +12 more
europepmc   +1 more source

Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins

FEBS Open Bio, EarlyView.
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó, Eszter Nagy‐Kanta, Soma Varga, Edit Andrea Jáger, Csaba István Pongor, Mária Laki, András József Laki, Zoltán Gáspári   +7 more
wiley   +1 more source

Flexible Parametric Accelerated Failure Time Models With Cure. [PDF]

Biom J
Akynkozhayev B, Christoffersen B, Liu X, Humphreys K, Clements M.   +4 more
europepmc   +1 more source

Thinking Inside the Bounds: Improved Error Distributions for Indifference Point Data Analysis and Simulation Via Beta Regression using Common Discounting Functions [PDF]

Mingang Kim, Mikhail N. Koffarnus, Christopher T. Franck   +2 more
openalex   +1 more source

Identification of amino acids essential for angulin‐1/3 binding of the tricellular tight junction binder, angubindin‐1

FEBS Open Bio, EarlyView.
Angubindin‐1 binds angulin‐1/‐3 at tricellular tight junctions, enhancing intestinal macromolecule permeation. Alanine scanning identified six essential residues (L562, L598, E638, V640, Y643, and K644) of angubindin‐1 critical for binding to angulin‐1/‐3 and permeation‐enhancing activity, providing insights for the development of targeted noninvasive ...
Taiki Kuzu, Yumi Iwashita, Keisuke Tachibana, Itsuki Nishino, Yuki Niwa, Atsuko Uyeda, Kazuki Matsuo, Masahiro Nagahama, Masuo Kondoh   +8 more
wiley   +1 more source

Insulin Resistance and Beta-Cell Function in the Context of Dyslipidemia in a Non-obese Indian Population With Type 2 Diabetes. [PDF]

Cureus
Tiwari D, Tripathi P, Kadam NS, Sharma B, Vyawahare A, Kathrikolly T, Ganla M, Saboo B.   +7 more
europepmc   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Modeling cognition through adaptive neural synchronization: a multimodal framework using EEG, fMRI, and reinforcement learning. [PDF]

Front Comput Neurosci
Hall R, Jackson M, Maleki M, Crogman HT.
europepmc   +1 more source