Molecular Oncology, EarlyView.Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien +7 more
wiley +1 more source
Beta-2-microglobulin in the assessment of renal function in full term newborns following perinatal asphyxia [PDF]
, 1989 Fernando Fernandez +6 more
openalex +1 more source
Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance
Molecular Oncology, EarlyView.Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren +4 more
wiley +1 more source
Beta 2 2 microglobulin in urine: not suitable for assessing renal tubular function. [PDF]
, 1983 M D Bastable
openalex +1 more source
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Diverse effects of beta-tubulin mutations on microtubule formation and function. [PDF]
, 1988 Tim C. Huffaker +2 more
openalex +1 more source
Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value
Molecular Oncology, EarlyView.The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song +13 more
wiley +1 more source
Effects of perturbation for transition operator of double-$β$ decay on nuclear matrix element, effective axial-vector current coupling, and half-life [PDF]
arXivWe calculate the nuclear matrix element (NME), effective axial-vector current coupling $g_A^\mathrm{eff}$, and half-life of the double-$\beta$ ($\beta\beta$) decay using the transition operator perturbed by the nuclear interaction. The correction terms for the NME are obtained by extending the hadron sector to a higher order in terms of the Rayleigh ...
arxiv
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Some generalized inequalities involving extended beta and gamma functions for several variables
Journal of Inequalities and ApplicationsRecently, extensions of the gamma and beta functions have been studied due to their appealing properties and wide range of applications in various scientific fields. This note aims to investigate generalized inequalities associated with the extended beta
S. Mubeen +4 more
doaj +1 more source