Results 231 to 240 of about 1,232,344 (309)

Chestnut-derived ellagitannins (FT50) protect against western diet-induced metabolic dysfunction and preserve beta cell function in mice. [PDF]

Front Endocrinol (Lausanne)
Klemen MS, Polšak N, Jakopiček J, Kovačič P, Kopecky J, Leitgeb EP, Kerčmar J, Bombek LK, Dolenšek J, Stožer A.   +9 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Identification of the ACTB p.Ser348Leu de novo variant in individuals with syndromic neonatal diabetes. [PDF]

EBioMedicine
Ahmed S, Lewis V, Russ-Silsby J, Wakeling MN, Thunander M, Vivanco M, Caswell R, Hattersley AT, Bowman P, Patel K, Flanagan SE, De Franco E.   +11 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The role of interleukin-1 beta as an early biomarker for renal dysfunction in Egyptian sickle cell disease patients. [PDF]

Ann Hematol
Nasr NM, Ghaffar NKAE, El Asmar SM, Saber YM.   +3 more
europepmc   +1 more source

Results on the Beta function

Sarajevo Journal of Mathematics, 2013
openaire   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

An Arduino-Based, Portable Prototype for the Recording and Analysis of EEG Signals to Support Self-Detection and Self-Monitoring of Stress. [PDF]

Sensors (Basel)
Baltzis S, Pagiatakis G, Voudoukis N, Papadakis A, Dritsas L, Uzunidis D.   +5 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Acylcarnitines and prediction of renal function decline in type 2 diabetes. [PDF]

BMJ Open Diabetes Res Care
Trischitta V, Fontana A, Shah H, Mastroianno M, Prehn C, De Cosmo S, Adamski J, Copetti M, Doria A, Menzaghi C.   +9 more
europepmc   +1 more source