Results 271 to 280 of about 13,428,920 (391)

Prolonged exposure of human pancreatic islets to high glucose concentrations in vitro impairs the beta-cell function. [PDF]

, 1992
Décio L. Eizirik, Gregory S. Korbutt, Claes Hellerström   +2 more
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

The contribution of a short electrocardiographic diastolic interval to diastolic dysfunction and HFpEF. [PDF]

BMC Cardiovasc Disord
van Ommen AMLN, Bear LR, Sampedrano CC, Onland-Moret NC, Cramer MJ, Rutten FH, Canto ED, Tulevski II, Somsen GA, Sweitzer NK, Coronel R, den Ruijter HM.   +11 more
europepmc   +1 more source

A 𝑞-beta integral on the unit circle and some biorthogonal rational functions [PDF]

, 1994
W. A. Al‐Salam, Mourad E. H. Ismail
openalex   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

Causal effects of obesity on estimated glomerular filtration rate: a Mendelian randomization and image data analysis study. [PDF]

Clin Kidney J
Ene P, Svensson MK, Strand R, Kullberg J, Ahlström H, Larsson A, Lind L.   +6 more
europepmc   +1 more source

Domains in microbial beta-1, 4-glycanases: sequence conservation, function, and enzyme families [PDF]

, 1991
Neil R. Gilkes, Bernard Henrissat, Douglas G. Kilburn, Robert C. Miller, R. A. J. Warren   +4 more
openalex   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

Cefepime-induced neurotoxicity. [PDF]

S Afr J Infect Dis
Taylor J, Gunter HM, Cohen K.
europepmc   +1 more source

305 Effect of two beta antagonists, bucinodolol and metoprolol, on pulmonary function in subjects with asthma

, 1985
P WELSH, C REED, Larry L. Jackson, R.J. Seidehamel   +3 more
openalex   +1 more source