Results 91 to 100 of about 386,471 (257)

Insights on the scale of leptogenesis from neutrino masses and neutrinoless double-beta decay

European Physical Journal C: Particles and Fields
We revisit the thermal leptogenesis scenario in the type-I seesaw framework featuring three heavy Majorana neutrinos with a hierarchical mass spectrum.
A. Granelli, K. Hamaguchi, M. E. Ramirez-Quezada, K. Shimada, J. Wada, T. Yokoyama   +5 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The alpha v beta 1 integrin functions as a fibronectin receptor but does not support fibronectin matrix assembly and cell migration on fibronectin

, 2020
R. L. Juliano, Zhuohua Zhang, Kristiina Vuori, Jeffrey S. Bauer, Erkki Ruoslahti, Alex O. Morla   +5 more
openalex   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Nonresonant renormalization scheme for twist-2 operators in SU(N) Yang–Mills theory

European Physical Journal C: Particles and Fields
Recently, the short-distance asymptotics of the generating functional of n-point correlators of twist-2 operators in SU(N) Yang–Mills (YM) theory has been worked out in Bochicchio et al. (Phys Rev D 108:054023, 2023).
Francesco Scardino
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Explicit expressions for the matrix exponential function obtained by means of an algebraic convolution formula

Electronic Journal of Differential Equations, 2014
We present a direct algebraic method for obtaining the matrix exponential function exp(tA), expressed as an explicit function of t for any square matrix A whose eigenvalues are known.
Jose Roberto Mandujano, Luis Verde-Star
doaj  

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Effect of Electro-Acupuncture (EA) and Manual Acupuncture (MA) on Markers of Inflammation in Knee Osteoarthritis

Journal of Pain Research, 2020
Guang-Xia Shi,1 Jian-Feng Tu,2 Tian-Qi Wang,2 Jing-Wen Yang,2 Li-Qiong Wang,2 Lu-Lu Lin,2 Yu Wang,1 Yong-Ting Li,1 Cun-Zhi Liu2 1Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical ...
Shi GX, Tu JF, Wang TQ, Yang JW, Wang LQ, Lin LL, Wang Y, Li YT, Liu CZ   +8 more
doaj