Results 101 to 110 of about 404,647 (233)

How New Chatbots Can Support Personalized Medicine. [PDF]

open access: yesHealthc Inform Res
Ramírez López LJ, Mora AMC.
europepmc   +1 more source

Delayformer: Spatiotemporal Transformation for Predicting High‐Dimensional Dynamics

open access: yesAdvanced Science, EarlyView.
Delayformer introduces a multivariate spatiotemporal transformation (mvSTI) that converts observed variables into delay‐embedded states and cross‐learns their dynamics using a shared Vision Transformer encoder. This approach, grounded in dynamical systems theory, simultaneously predicts all variables in high‐dimensional systems, outperforming state‐of ...
Zijian Wang, Peng Tao, Luonan Chen
wiley   +1 more source

MCUB Inhibits PRKN‐Dependent Mitophagic Degradation of PD‐L1 to Promote Immune Evasion in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
In bladder cancer, the overexpression of MCUB not only reduces mitochondrial calcium influx but also facilitates its binding to PRKN at Arg51, both mechanisms contribute to the impairment of PRKN‐mediated mitophagy. Consequently, the degradation of PD‐L1 is suppressed, leading to its stable expression on the tumor cell surface.
Yuan Huang   +13 more
wiley   +1 more source

The High‐Altitude Adaptation Characteristics of Microbiota‐Host Cross‐Talk in Yak Gastrointestinal Track

open access: yesAdvanced Science, EarlyView.
In this study, a single‐cell atlas of 117,019 yak gastrointestinal cells across 54 subtypes identified HNF4A and SREBF2 as key transcription factors targeting MYO6 gene. Cross‐species and multi‐omics analyses reveals epithelial cells as key regulators that, through interactions with microbes, particularly Bacillus, facilitate flexible energy supply and
Chun Huang   +12 more
wiley   +1 more source

Autonomous Polymer Frameworks for Sustainable Tissue‐Interfaced Plastic Bioelectronics

open access: yesAdvanced Science, EarlyView.
This review focuses on plastic bioelectronic systems integrated with autonomous polymer frameworks (auto‐POFs) and summarizes recent progress in this field. It provides an in‐depth analysis of the design strategies and operational mechanisms of auto‐POFs, highlighting their pivotal role in enhancing the sustainability and interfacial adaptability of ...
Elvis K. Boahen   +8 more
wiley   +1 more source

Pediatric cochlear implantation: The impact of frequency-to-place mismatch after a three-year follow-up. [PDF]

open access: yesPLoS One
Hamed N   +6 more
europepmc   +1 more source

Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex

open access: yesAdvanced Science, EarlyView.
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano   +11 more
wiley   +1 more source

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