Results 181 to 190 of about 4,044,085 (243)

From Folding Mechanics to Robotic Function: A Unified Modeling Framework for Compliant Origami

Advanced Science, EarlyView.
A geometry‐consistent DDG framework captures compliant origami deformation from rigid‐like folding to soft panel bending. By tuning crease and panel stiffness, bistable snap‐through responses transform into smooth monostable deformation, enabling programmable stability and robot‐scale locomotion.
Bohan Zhang, Bo Wang, Huajiang Ouyang, Zhigang Wu, Haohao Bi, Jiawei Xu, Mingchao Liu, Weicheng Huang   +7 more
wiley   +1 more source

β2-adrenergic receptor stimulation drives differentiation of human adipose-derived mesenchymal stem cells into beige adipocytes. [PDF]

Adipocyte
Maekawa K, Yokoyama F, Tsutsumi R, Tateishi A, Maeda A, Tateishi N.   +5 more
europepmc   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Stochastic Entanglement of Deterministic Origami Tentacles For Robust Robotic Grasping

Advanced Science, EarlyView.
This study introduces an origami tentacle gripper to robustly grasp objects‐in air, underwater, and even in orbital space‐by exploiting a synergy between local, deterministic deformation programming and global, stochastic entanglements. A single origami tentacle can be designed to coil with a simple tendon pull.
Alec Boron, Bokun Zheng, Ziyang Zhou, Noel Naughton, Suyi Li   +4 more
wiley   +1 more source

From clinical trial to clinical experience: Lecanemab therapy in a real-world case series. [PDF]

Alzheimers Dement (Amst)
Sonson M, Yadollahikales G, Flores A, Lasner I, Lee S, Tan Z, Quach C, Kremen S.   +7 more
europepmc   +1 more source

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

Advanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl, David Holubek, Klaus Speck, Raphael Wildermuth, Franz‐Lucas Haut, Stephan Permann, Immanuel Plangger, Christian Steinborn, Zhigang Rao, Danilo D'Avino, Ida Cerqua, Julia Stadler, Fiorentina Roviezzo, Peter Schlenke, Anita Siller, Harald Schennach, Solveigh C. Koeberle, Eva‐Maria Pferschy‐Wenzig, Antonietta Rossi, Thomas Magauer, Andreas Koeberle   +20 more
wiley   +1 more source

Epilepsy clinic analytics: leveraging EMR reporting tools to characterize center volume and complexity. [PDF]

Front Neurol
Arya V, Mazumder AG, Nnamani M, Abboud MA, Lee SC, Guzman MS, Krishnan V.   +6 more
europepmc   +1 more source

Measuring the Time-Scale-Dependent Information Flow Between Maternal and Fetal Heartbeats During the Third Trimester: Impact of Fetal Sex and Maternal Chronic Stress. [PDF]

Biology (Basel)
Garnier NB, Molinet MS, Antonelli MC, Lobmaier SM, Frasch MG.   +4 more
europepmc   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Probabilistic MIC modelling for AMR risk assessment. [PDF]

EFSA J
Baños AP, Stefanou CR, Stathas L, Papagianeli SD, Ordóñez AÁ, Doulgeraki A, Koutsoumanis K.   +6 more
europepmc   +1 more source