In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He +20 more
wiley +1 more source
Maternal mental health and its influence on children's early development: Evidence from Khyber Pakhtunkhwa, Pakistan. [PDF]
Hentschel E +6 more
europepmc +1 more source
Human ancestries simulation and inference: a review of ancestral recombination graph-based approaches. [PDF]
Fournier P, Larribe F.
europepmc +1 more source
Sub-inhibitory concentrations of metronidazole alter the proteomic profile and biological effects of extracellular vesicles from Clostridioides difficile. [PDF]
Ran Z, Ruan X, Pan Y, Wang L, Li G.
europepmc +1 more source
Magnetoencephalography study of the Xingnao Kaiqiao acupuncture during acupuncture and language task states in healthy volunteers: a single-blind, randomized, sham-controlled trial protocol. [PDF]
Sun C +14 more
europepmc +1 more source
Prompt Engineering of Large Language Models for Medication Dose Calculation. [PDF]
Weaver M +4 more
europepmc +1 more source
Roadmap for using large language models (LLMs) to accelerate cross-disciplinary research with an example from computational biology. [PDF]
Ke R, Ribeiro RM.
europepmc +1 more source
On Type Systems for Object-Oriented Database Programming Languages
ACM Computing Surveys, 2002Duane Allen Szafron +2 more
exaly
The Scratch Programming Language and Environment
ACM Transactions on Computing Education, 2010Mitchel Resnick +2 more
exaly

