Results 51 to 60 of about 406,411 (253)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
A comparison of joint species distribution models for percent cover data
Methods in Ecology and EvolutionJoint species distribution models (JSDMs) have gained considerable traction among ecologists over the past decade, due to their capacity to answer a wide range of questions at both the species‐ and the community‐level.
Pekka Korhonen +4 more
doaj +1 more source
Modeling the Household Income Expended on Food in Egypt: A Beta Regression Approach [PDF]
The Egyptian Statistical Journal, 2014 The Beta distribution is a highly flexible parametric distribution, able to accommodate both unimodal and bimodal densities with varying severity of skewness.
Magda Mohamed Mohamed Hagag
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μσ2-Beta and μσ2-Beta Binomial Regression Models
Revista Colombiana de Estadística, 2023 This paper proposes new parameterizations of the beta and beta binomial distributions as functions of the mean and variance parameters. From these new parameterizations, new beta and beta binomial linear regression models are formulated by assuming that appropriate real functions of the mean and variance follow linear regression structures.
openaire +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Implications of land-use change on forest carbon stocks in the eastern United States
Environmental Research Letters, 2017 Given the substantial role that forests play in removing CO _2 from the atmosphere, there has been a growing need to evaluate the carbon (C) implications of various forest management and land-use decisions.
Joshua Puhlick +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Beta Restricted Regression Estimators: Simulation and Application [PDF]
The Egyptian Statistical JournalStatistics is the science that aims to collect and analyze data. In data analysis, researchers need to collect all information that serves their study.
Alaa Abd-Elmegaly
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
On the maximum likelihood estimator in the generalized beta regression model [PDF]
Opuscula Mathematica, 2012 The subject of this article is to present the beta - regression model, where we assume that one parameter in the model is described as a combination of algebraically independent continuous functions.
Jerzy P. Rydlewski, Dominik Mielczarek
doaj +1 more source