Results 161 to 170 of about 36,735 (203)

Accelerated atherosclerosis in beta-thalassemia

American Journal of Physiology-Heart and Circulatory Physiology, 2023
This work definitively shows for the first time that beta-thalassemia leads to accelerated atherosclerosis. We demonstrated that intravascular hemolysis is a prominent feature in beta-thalassemia and the resulting increases in free heme are mechanistically relevant.
Julian Hurtado, Hassan Sellak, Giji Joseph, Caitlin V. Lewis, Crystal R. Naudin, Sergio Garcia, James Robert Wodicka, David R. Archer, W. Robert Taylor   +8 more
openaire   +2 more sources

β-Thalassemia Mutations in Corsica

Hemoglobin, 2000
Screening of beta thalassemia mutations in Corsica.
Varesi L, Vina G, Memmi M, Marongiu MF, Ristaldi MS   +4 more
openaire   +5 more sources

Neurological complications of beta-thalassemia

Annals of Hematology, 2015
The thalassemias are the most common single gene disorder in the world. Over the last years, several reports have demonstrated neurological complications in beta-thalassemia patients. In most cases, these complications remained subclinical and were detected only during neuropsychological, neurophysiological, or neuroimaging evaluation.
P. Nemtsas, M. Arnaoutoglou, V. Perifanis, E. Koutsouraki, A. Orologas   +4 more
openaire   +2 more sources

Hypertriglyceridemia in homozygous beta thalassemia

The Journal of Pediatrics, 1975
A case of hypertriglyceridemia in association with homozygous beta-thalassemia in an 11-month-old female infant is reported. The hypertriglyceridemia proved to be secondary, as it was indicated by clinical features as well as laboratory findings. Attention is called to a possible alteration of lipid metabolism in association with thalassemia major.
M R, Ameri, M, Alebouyeh, M, Ziai, R B, Conn   +3 more
openaire   +2 more sources

Pycnodysostosis with heterozygous beta-thalassemia

Pediatric Radiology, 1977
A 6-year follow-up of a Greek girl with pycnodysostosis associated with heterozygous beta-thalassemia is reported. Active rickets in infancy was superimposed on pycnodysostosis. In the family the autosomal recessive disease, pycnodysostosis, appeared in two of three siblings in combination with the autosomal dominant disease, thalassemia minor.
G, Benz, E, Schmid-Rüter
openaire   +2 more sources

C3 Polymorphism in Beta-Thalassemia

Acta Haematologica, 2009
The distribution of phenotypes and gene frequencies of the third component of complement (C3) were studied in 106 β-thalassemic patients and in 112 carriers of the β-thalassemia trait. A statistically significant association was found between the C3F gene and homozygous β-thalassemia.
A, Germenis, M, Kalantzi, A, Karamerou, C, Politi, A, Fertakis   +4 more
openaire   +2 more sources

Ophthalmic Evaluation in Beta-Thalassemia

The Indian Journal of Pediatrics, 2017
To determine the association of ocular manifestations in beta-thalassemia with the patient's age, blood transfusion requirements, average serum ferritin and dose and duration of iron chelation therapy.Sixty multi-transfused beta thalassemia patients of 12 to 18 y of age on chelation therapy were included in this cross-sectional analysis. Structural and
Rashid H, Merchant, Hrishikesh, Punde, Neepa, Thacker, Deepak, Bhatt   +3 more
openaire   +2 more sources

Gene addition for beta thalassemia

Annals of the New York Academy of Sciences, 2023
Abstract Individuals with transfusion‐dependent beta thalassemia require a high burden of care and experience significant morbidity from the underlying disease and its treatment, which negatively impact the quality of life.
openaire   +2 more sources

[Beta-Thalassemia in Poland. I. Mediterranean mutations in beta-thalassemia].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006
The aim of the present investigation was to verify a common view that thalassemia in Poland is a very rare disease.600 patients (270 male and 330 female) aged 2-85 years with microcytosis and no evidence of iron deficiency were examined for beta-thalassemia. Hemoglobin A2 and hemoglobin F and bilirubin were evaluated.
Ewa, Zdebska, Angelika, Krawcewicz, Anna, Adamowicz-Salach, Teresa, Jackowska, Barbara, Tejza, Wojciech, Strojny, Maria, Kuliszkiewicz-Janus, Urszula, Mokras, Jerzy, Kościelak   +8 more
openaire   +2 more sources

Beta-Thalassemia Syndromes and Pregnancy

Obstetrical & Gynecological Survey, 1994
The literature relating to homozygous beta-thalassemia and the problems these patients have during their pregnancy is reviewed and another case report of a twin pregnancy in a homozygous beta-thalassemia individual is included. The majority of cases described refer to the intermedia clinical form of the hematological problem because patients with ...
C, Savona-Ventura, F, Bonello
openaire   +2 more sources