Results 251 to 258 of about 45,973 (258)

Structural prediction of chimeric immunogen candidates to elicit targeted antibodies against betacoronaviruses. [PDF]

PLoS Comput Biol
Simpson J, Kasson PM.
europepmc   +1 more source

Glycosylphosphatidylinositol biosynthesis functions as a conserved host defense pathway against coronaviruses via regulation of LY6E. [PDF]

PLoS Pathog
Ma Y, Feng F, Feng H, Ma X, Wang Z, Han Y, Zhu Y, Wang Y, Gao Z, Zhang Y, Ding Q, Zhao J, Zhang R.   +12 more
europepmc   +1 more source

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Microtubule depolymerization limits porcine betacoronavirus PHEV replication

Veterinary Microbiology, 2022
Porcine hemagglutinating encephalomyelitis virus (PHEV) is a typical neurotropic betacoronavirus causing digestive disease and/or neurological dysfunction in neonatal pigs. Actin filaments have been identified to implicate in PHEV invasion, but the effects of viral infection on microtubules (MTs) cytoskeleton are unknown.
Qianyu, Zhou, Yungang, Lan, Yifei, Tang, Jiyu, Guan, Kui, Zhao, Feng, Gao, Wenqi, He, Zi, Li   +7 more
openaire   +2 more sources

First Molecular Evidence for Bat Betacoronavirus in Mindanao

Philippine Journal of Science, 2019
Coronaviruses (CoVs) are common agents of respiratory and gastrointestinal tract infections but are also considered as important emerging infectious disease (EID) agents that have led to global epidemics of severe respiratory disease. Human CoV EIDs have been proposed to have originated from bat CoVs (BtCoV).
Tampon, Nikki Vanesa, Rabaya, Ysabela Marie, Malbog, Kameela Monique, Burgos, Sammer, Bacus, Michael, Libre, Kemuel, Valila, Agape Shelley, Achondo, Marion John Michael, Siarot Onggo, Lowela, E. Murao, Lyre Anni   +9 more
openaire   +1 more source

The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammation

Science Signaling
Coronaviruses rely on host proteases to activate the viral spike protein, which facilitates fusion with the host cell membrane and the release of viral genomic RNAs into the host cell cytoplasm.
Hyunjoon Kim, Yeonglim Kang, Semi Kim, Dongbin Park, Seo-Young Heo, Ji-Seung Yoo, Isaac Choi, Monford Paul Abishek N, Jae-Woo Ahn, Jeong-Sun Yang, Nayeon Bak, Kyeong Kyu Kim, Joo-Yeon Lee, Y. Choi   +13 more
semanticscholar   +1 more source

Angiotensin-(1-7) decreases inflammation and lung damage caused by betacoronavirus infection in mice.

Inflammation Research
E. B. S. Lima, Antônio Felipe S Carvalho, Isabella Zaidan, A. H. A. Monteiro, Camila Cardoso, Edvaldo S Lara, F. S. Carneiro, L. C. Oliveira, Filipe Resende, F. R. Santos, Luiz P. Souza-Costa, I. Chaves, C. Queiroz-Junior, R. C. Russo, Robson A S Santos, Luciana P. Tavares, M. M. Teixeira, Vivian V Costa, L. Sousa   +18 more
semanticscholar   +1 more source