A multicenter clinical trial was performed to compare the efficacy and safety of Ginkgo biloba extract EGb 761 and betahistine at recommended doses in patients with vertigo. One hundred and sixty patients (mean age 58 years) were randomly assigned to double‐blind treatment with EGb 761 (240 mg per day) or betahistine (32 mg per day) for 12 weeks. An 11‐
Larysa Sokolova +3 more
wiley +1 more source
Effects of Betahistine on the Development of Vestibular Compensation After Unilateral Labyrinthectomy in Rats [PDF]
Background: Vestibular compensation (VC) after unilateral labyrinthectomy (UL) consists of the initial and late processes. These processes can be evaluated based on the decline in the frequency of spontaneous nystagmus (SN) and the number of MK801 ...
Tadashi Kitahara +2 more
exaly +4 more sources
Transbuccal Delivery of Betahistine Dihydrochloride From Mucoadhesive Tablets With a Unidirectional Drug Flow: In Vitro, Ex Vivo and in Vivo Evaluation [PDF]
Mohamed A El-Nabarawi,1 Adel A Ali,2 Heba M Aboud,2 Amira H Hassan,2 Amany H Godah2 1Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, 2Department of Pharmaceutics, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt ...
Heba M Aboud +2 more
exaly +4 more sources
A novel transdermal nanoethosomal gel of betahistine dihydrochloride for weight gain control: in-vitro and in-vivo characterization [PDF]
Shahira F El-Menshawe,1 Adel Ahmed Ali,1 Abdelkhalk Ali Halawa,2 Ahmed SG Srag El-Din2 1Department of Pharmaceutics and Industrial Pharmacy, Beni-Suef University, Beni-Suef, 2Department of Pharmaceutics and Clinical Pharmacy, Nahda University, Beni-Suef,
El-Menshawe SF +3 more
doaj +2 more sources
A pilot study on early microgliogenesis following unilateral vestibular neurectomy: A key player in vestibular compensation? [PDF]
Following unilateral vestibular damage, several behavioral deficits arise, referred to as vestibular syndrome. At the central level the vestibular syndrome is associated with an imbalance in neuronal activity between the two vestibular nuclei (VN).
Jessica Trico +5 more
doaj +2 more sources
Betahistine Dihydrochloride With and Without Early Vestibular Rehabilitation for the Management of Patients With Balance Disorders Following Head Trauma: A Preliminary Randomized Clinical Trial [PDF]
Naguib MB, Madian YT.
exaly +2 more sources
The Utility of Betahistine Dihydrochloride, a Structural Analog of Histamine, in Clozapine-associated Daytime Sedation: A Case Series [PDF]
Shikha Agarwal +3 more
doaj +2 more sources
Comments on: “The Utility of Betahistine Dihydrochloride, a Structural Analog of Histamine, in Clozapine-Associated Daytime Sedation: A Case Series” [PDF]
Santhini Ajay +2 more
doaj +2 more sources
A comparative study on the response to Epley’s maneuver and betahistine dihydrochloride management among patients with benign paroxysmal positional vertigo [PDF]
The objective of this study is to evaluate the effectiveness of Epley’s maneuver and Betahistine dihydrochloride on the improvement of patients from BPPV and to comparing the outcome of the use of Betahistine dihydrochloride with the outcome of the use ...
Zaid I. Alsareeh
doaj +1 more source
Betahistine exerts a dose-dependent effect on cochlear stria vascularis blood flow in guinea pigs in vivo. [PDF]
ObjectiveBetahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière's disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated.
Fritz Ihler +5 more
doaj +1 more source

