Approaches in topical ocular drug delivery and developments in the use of contact lenses as drug-delivery devices [PDF]
, 2017 The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Drug-delivery approaches have diversified over the last two decades with the emergence of nanotechnologies,
Acheampong A +17 more
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Carbohydrate Polymer Technologies and ApplicationsRow carpentry waste wood flour, constituted of poplar (∼60 %) and fir (∼30 %) biomass, was subjected for the first time to microwave-assisted deep eutectic solvent (DES) treatment, with the purposes of solubilizing lignin and hemicellulose, leaving ...
Giovanni Cisternino +4 more
doaj +1 more source
Pharmacological manipulation of L-carnitine transport into L6 cells with stable overexpression of human OCTN2 [PDF]
, 2018 .: The high-affinity Na+-dependent carnitine transporter OCTN2 (SLC22A5) has a high renal expression and reabsorbs most filtered carnitine. To gain more insight into substrate specificity of OCTN2, we overexpressed hOCTN2 in L6 cells and characterized ...
Brooks, H. +6 more
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Myosin-cross-reactive antigen (MCRA) protein from Bifidobacterium breve is a FAD-dependent fatty acid hydratase which has a function in stress protection [PDF]
, 2011 peer-reviewedBackground The aim of this study was to determine the catalytic activity and physiological role of myosin-cross-reactive antigen (MCRA) from Bifidobacterium breve NCIMB 702258. MCRA from B.
Alena Liavonchanka +7 more
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Conductivity and bonding structures of aqueous solutions of imidazolium and choline ionic liquids
Journal of Ionic LiquidsIonic liquids (ILs) have gained recognition as a potential alternative to traditional solvents due to their environmentally friendly properties. The ease of handling and higher conductivities of aqueous solutions of ILs has also stimulated research of ...
Georgina Moss +2 more
doaj +1 more source
SNAC-tag for sequence-specific chemical protein cleavage. [PDF]
, 2019 Site-specific protein cleavage is essential for many protein-production protocols and typically requires proteases. We report the development of a chemical protein-cleavage method that is achieved through the use of a sequence-specific nickel-assisted ...
Dang, Bobo +5 more
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A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells [PDF]
, 2017 Recent advances in fluorescent ligand technology have enabled the study of G protein-coupled receptors in their native environment without the need for genetic modification such as addition of N-terminal fluorescent or bioluminescent tags.
Antonioli +59 more
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The growth of paracoccus halodenitrificans in a defined medium [PDF]
A synthetic medium, consisting of inorganic salts and any of a number of carbon sources, supported the aerobic growth of Paracoccus halodenitrificans when supplemented with thiamine.
Hochstein, L. I., Tomlinson, G. A.
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Impacts of plant-based foods in ancestral hominin diets on the metabolism and function of gut microbiota in vitro [PDF]
, 2014 Ancestral human populations had diets containing more indigestible plant material than present-day diets in industrialized countries. One hypothesis for the rise in prevalence of obesity is that physiological mechanisms for controlling appetite evolved ...
Barraclough, Timothy G. +8 more
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A fast genetically encoded fluorescent sensor for faithful in vivo acetylcholine detection in mice, fish, worms and flies [PDF]
, 2020 Here we design and optimize a genetically encoded fluorescent indicator, iAChSnFR, for the ubiquitous neurotransmitter acetylcholine, based on a bacterial periplasmic binding protein.
Borden, Philip M. +4 more
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