Results 81 to 90 of about 17,068 (209)
ABSTRACT Eosinophilic fasciitis (EF) and morphea are rare sclerosing connective tissue disorders, and there remains debate about whether these entities are pathologically distinct or related. This case report describes the successful treatment of an adolescent patient who developed progressive morphea plaques while being treated with systemic ...
Daphne M. Cheung +5 more
wiley +1 more source
ABSTRACT Although topical corticosteroids are known triggers in the development of perioral dermatitis (PD), investigation into inhalant and nasal corticosteroid preparations, commonly used to manage allergic rhinitis and asthma, remains limited to case series.
Taylor Merkle +4 more
wiley +1 more source
Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro +2 more
wiley +1 more source
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Physiological and anatomical determinants of placental drug transfer
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
Ultrasound‐Guided Nerve Hydrodissection for Sural Nerve Injury: A Case Report and Review of the Literature [PDF]
ABSTRACT Sural nerve entrapment is a relatively uncommon cause of lateral ankle and foot pain and sensory disturbance. Conventional management generally lacks direct, targeted intervention at the site of nerve injury. We report a case of a 33‐year‐old male patient who developed sural neuropathy secondary to a right ankle sprain. Diagnosis was confirmed
Zhu M +8 more
europepmc +2 more sources
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
ABSTRACT Preeclampsia significantly contributes to maternal and perinatal morbidity and mortality, with twin pregnancies increasing this risk. Severe preeclampsia often requires pregnancy termination to protect maternal health. We report two cases of IVF‐conceived twin pregnancies complicated by early preeclampsia. The first case involved a 34 year‐old
Fatemeh Golshahi +8 more
wiley +1 more source
Interdisciplinary management of a viable term abdominal ectopic pregnancy
Abstract Introduction Abdominal ectopic pregnancies are rare and associated with increased maternal morbidity and mortality. As the majority are diagnosed early in gestation, there are few reports of management of advanced abdominal ectopic pregnancies. Case A 41‐year‐old gravida 2 para 1 presented with fatigue and a known left ovarian cyst.
Sarena Hayer +9 more
wiley +1 more source
COVID‐19 Mortality in Swedish Intensive Care Units: A Multicenter Survival Analysis
ABSTRACT Background Mortality among critically ill COVID‐19 patients has varied globally. In Sweden, geographic differences in mortality have also been observed. The current study aimed to determine whether mortality differences persist after adjusting for differences in case‐mix, and to identify potential independent factors contributing to regional ...
Gustaf Forsberg +10 more
wiley +1 more source

