Results 81 to 90 of about 17,117 (211)
Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States
Veterinary Dermatology, EarlyView.ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro +2 more
wiley +1 more source
Clinically relevant intra‐articular corticosteroid doses impair equine osteoclast function in vitro
Veterinary Surgery, EarlyView.Abstract Objective To assess the effects of clinically relevant doses of commonly employed intra‐articular corticosteroids—specifically, triamcinolone acetonide (TCA), methylprednisolone acetate (MPA), and combination of betamethasone acetate and betamethasone sodium phosphate (BM)—on equine osteoclasts.
Gwladys Malek +4 more
wiley +1 more source
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
The Journal of Physiology, EarlyView.Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Physiological and anatomical determinants of placental drug transfer
The Journal of Physiology, EarlyView.Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade +13 more
wiley +1 more source
Acta Paediatrica, Volume 115, Issue 9, Page 1847-1860, September 2026.ABSTRACT Aims and Methods Advances in neonatal care have extended borderline survival to 22–24 post‐conceptional weeks. Present review discusses approaches for prolonging short pregnancies and prevention of serious morbidities in extremely premature infants born before 28 weeks of pregnancy.
Mikko Hallman
wiley +1 more source
Brain and Behavior, Volume 16, Issue 8, August 2026.ABSTRACT Background Tuberculous meningitis (TBM) carries a case fatality rate of up to 50% in resource‐limited settings despite standard anti‐tuberculosis therapy. Adjunctive corticosteroids are widely recommended, yet their effect on mortality and safety across diverse populations remains imprecisely defined.
Ayesha Younas +14 more
wiley +1 more source
Yellow Palm Discoloration After Phenol Exposure
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Phenol exposure typically causes irritant contact dermatitis with yellow‐brown discoloration. A worker developed characteristic discoloration followed by rapidly evolving distant eruptions consistent with an id reaction after phenol exposure. Symptoms resolved with conservative treatment and elimination of exposure.
Makoto Kondo +3 more
wiley +1 more source
National Board of Examinations Journal of Medical SciencesIntroduction: Hypergranulation tissue is an excessive proliferation of immature granulation tissue that rises above the wound surface, delaying re-epithelialization.
Alakhananda Chandranaath +2 more
doaj +1 more source