Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
ANALISIS PENGARUH ILLUSION OF CONTROL, BETTER-THAN-AVERAGE, MISCALIBRATION, DESIRABILITY BIAS DAN PENDIDIKAN TERHADAP PERILAKU OVERCONFIDENCE (Studi Kasus pada Mahasiswa Ekonomi & Non-Ekonomi Universitas Diponegoro dalam Pengambilan Keputusan Keuangan) [PDF]
Overconfidence is a behaviour where someone, feeling very confident about the things, ignoring unimportant factors, taking excessive risk because of their abilities.
ARFINTO, Erman Denny, KURNIAWAN, Andre
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The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The impact of inflation and unemployment on subjective personal and country evaluations [PDF]
The authors use data from the Gallup World Poll to analyze what determines individual assessments of past, present, and future personal and country well-being.
Néstor Gándelman +1 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Halocarbon refrigerants have been scheduled for total phase out because they contributed significantly to the two major global environmental problems - ozone layer depletion and global warming.In this study, the performances of the environmentally ...
F. O. Borokinni +2 more
doaj +1 more source
Bank Scale Economies, Mergers, Concentration, and Efficiency: The U.S. Experience [PDF]
There have been numerous econometric studies of bank scale and scope economies, efficiency, mergers, and market structure and performance in U.S. banking. According to the authors, these studies have come to the following conclusions: Scale: For the very
Allen Berger, David Humphrey
core
Profitability of Organic Farming Systems [PDF]
The majority of the farmers I meet, that are interested in organic farming are financially driven. It is important that the message on financial returns from organic farming is clear.
McDonnell, James
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We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

