Results 111 to 120 of about 40,952 (301)
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang +7 more
wiley +1 more source
Urban in-betweenness: Rotterdam / Mexico City
‘Urban in-betweenness’ offers a short reflection on the way conflicts on a global scale are perceived on an individual level within the urban context and how this will have spatial repercussions.
Moniek Driesse, Isaac Landeros
doaj +1 more source
ABSTRACT The E2 domain of amyloid precursor protein (APP_E2) plays a central role in the protein's function. We reinvestigate how the missense mutation, ΔH382L, affects the domain's thermal stability and ligand binding propensity through differential scanning fluorometry.
Sphamandla Ndlovu +4 more
wiley +1 more source
Positivity, Betweenness, and Strictness of Operator Means
An operator mean is a binary operation assigned to each pair of positive operators satisfying monotonicity, continuity from above, the transformer inequality, and the fixed-point property.
Pattrawut Chansangiam
doaj +1 more source
ABSTRACT Hydrogen‐bond networks are central to protein function, but most network analyses rely on static representations that neglect how interactions evolve in time. Here, we introduce a framework that combines instantaneous and temporal graph analysis of hydrogen‐bond networks derived from molecular dynamics (MD) trajectories to quantify ligand ...
Tandac F. Guclu +2 more
wiley +1 more source
ABSTRACT Allosteric communication is fundamental to the function of proteins, but identifying the residue‐level pathways through which signals travel and their directionality is still a major challenge. Here we present a multi‐metric information‐theoretic framework that identifies candidate allosteric communication pathways from a single protein ...
Aysima Hacisuleyman, Dirk Fasshauer
wiley +1 more source
Caring Behaviours in Nursing: A Bibliometric Analysis of Global Research Trends and Knowledge Structure. [PDF]
ABSTRACT Background Caring behaviours constitute one of the most visible ways in which “caring” is translated into everyday nursing practice, yet the field has become increasingly heterogeneous across settings, outcomes, and conceptual traditions. A field‐level map is therefore needed to clarify how the literature has evolved and where it is currently ...
Özkan İ, Taylan S.
europepmc +2 more sources
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei +4 more
wiley +1 more source
First-order logic with metric betweenness – the case of non-definability of some graph classes
The metric betweenness of a connected graph and arbitrary graphs is FO definable. Moreover, several interesting classes of graphs with strong distance properties are shown to be FO definable using metric betweenness.
Jeny Jacob, Manoj Changat
doaj +1 more source
The Dynamics of Closeness and Betweenness [PDF]
Although both betweenness and closeness centrality are claimed to be important for the effectiveness of someone’s network position, it has not been comprehensively studied which networks emerge if actors strive to optimize their centrality in the ...
Buechel, Berno, Buskens, Vincent
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