Results 31 to 40 of about 11,630 (189)

Histories in bone: Navigating the ethical landscape of human skeletal collections in South Africa

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Provenance is at the center of addressing the complicated ethical stewardship of legacy human skeletal collections. Many South African (SA) health science institutions have skeletal collections. While the history of the collections and the demographics of the skeletons have been reported, the provenance of the individuals within the ...
Quenth Chinenere   +2 more
wiley   +1 more source

Integrating multiple vehicle drivetrains into an energy system simulation model for Japan

open access: yesScience and Technology for Energy Transition
To reduce the impact of climate change, the Japanese economy has set mitigation goals that include the decarbonisation of the energy sector and the electrification of transport.
Knüpfer K.   +4 more
doaj   +1 more source

Efficacy and safety of trifluridine/tipiracil plus bevacizumab and trifluridine/tipiracil or regorafenib monotherapy for chemorefractory metastatic colorectal cancer: a retrospective study

open access: yesTherapeutic Advances in Medical Oncology, 2021
Background: The C-TASK-FORCE phase I/II and Danish randomized phase II trials reported the promising efficacy of trifluridine/tipiracil (TAS102) plus bevacizumab (BEV) in patients with chemorefractory metastatic colorectal cancer (mCRC).
Keigo Chida   +10 more
doaj   +1 more source

Efficacy and safety of bevacizumab in the treatment of adult gliomas: a systematic review and meta-analysis

open access: yesBMJ Open, 2021
Objective To assess the efficacy and safety of bevacizumab (BEV) in patients with glioma.Design Systematic review and meta-analysis.Participants Adults aged 18 years and above, whose histology was confirmed to be malignant glioma.Primary and secondary ...
Kai Wang   +4 more
doaj   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

open access: yesBiotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady   +6 more
wiley   +1 more source

Outcomes and prognoses of patients with ovarian cancer using bevacizumab: 6-year experience in a tertiary care hospital of northern Taiwan.

open access: yesPLoS ONE, 2017
PurposeBevacizumab (BEV) has been used for ovarian cancer (OC) for years in Taiwan, but the associated data related to outcome is scant. This retrospective study reviewed patients with OC treated with BEV and analyzed their results.Patients and ...
Wei-Chun Chen   +8 more
doaj   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

How do users adapt to a short-range battery electric vehicle in a two-car household? Results from a trial in Sweden

open access: yesTransportation Research Interdisciplinary Perspectives, 2022
We supplied 25 two-car households with a short-range battery electric vehicle (BEV) to study their adaptation to a BEV replacing one of their conventional cars.
Niklas Jakobsson   +2 more
doaj   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

open access: yesBiotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Same‐Day Discharge After Transcatheter Aortic Valve Implantation: Who, When, and How?

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT The burden of severe aortic stenosis requiring treatment is growing due to ageing populations. This places increased demands on health resources due to the growing number of transcatheter aortic valve implantation (TAVI) procedures and hospital bed occupancy.
Hilal Khan   +8 more
wiley   +1 more source

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