Results 151 to 160 of about 5,577,820 (369)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Dark matter casts light on the early Universe

open access: yesJournal of High Energy Physics, 2018
We show how knowledge of the cold dark matter (CDM) density can be used, in conjunction with measurements of the parameters of a scenario for beyond the Standard Model (BSM) physics, to provide information about the evolution of the Universe before Big ...
A. Arbey   +3 more
doaj   +1 more source

Anatomy of $\varepsilon'/\varepsilon$ beyond the Standard Model

open access: yes, 2019
We present for the first time a model-independent anatomy of the ratio $\varepsilon'/\varepsilon$ in the context of the $\Delta S = 1$ effective theory with operators invariant under QCD and QED and in the context of the Standard Model Effective Field ...
Aebischer, Jason   +3 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Electroweak and Higgs boson internal bremsstrahlung. General considerations for Majorana dark matter annihilation and application to MSSM neutralinos

open access: yesJournal of High Energy Physics, 2017
It is well known that the annihilation of Majorana dark matter into fermions is helicity suppressed. Here, we point out that the underlying mechanism is a subtle combination of two distinct effects, and we present a comprehensive analysis of how the ...
Torsten Bringmann   +3 more
doaj   +1 more source

Beyond the Standard Model’ 17

open access: yes, 2018
We discuss the status of the Standard Model (SM): the principles; the Lagrangian; the problems; open questions and the ways beyond. Then we consider possible physics beyond the SM: New symmetries (Gauge, SUSY); New particles (gauge, axion, superpartners); New dimensions (extra, large, compact, etc) or a New Paradigm (strings, branes, gravity).
openaire   +2 more sources

European Code Against Cancer, 5th edition – hormone replacement therapy, other common medical therapies and cancer

open access: yesMolecular Oncology, EarlyView.
The 5th edition of the European Code Against Cancer (ECAC5) contains 14 recommendations on cancer prevention. Here, we update the cancer prevention recommendations regarding the use of hormone replacement therapy (HRT), which is positioned as recommendation number 13 of the ECAC5.
Mangesh A. Thorat   +18 more
wiley   +1 more source

Starobinsky-like inflation and soft-SUSY breaking

open access: yesJournal of High Energy Physics, 2019
We study a version of Starobinsky-like inflation in no-scale supergravity (SUGRA) where a Polonyi term in the hidden sector breaks supersymmetry (SUSY) after inflation, providing a link between the gravitino mass and inflation.
Stephen F. King, Elena Perdomo
doaj   +1 more source

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