Results 181 to 190 of about 5,330,848 (365)
Future High Precision Experiments and New Physics Beyond Standard Model [PDF]
Mingxing Luo
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RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha+10 more
wiley +1 more source
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban+12 more
wiley +1 more source
Lepton flavor violating decays of Higgs bosons beyond the standard model [PDF]
J. Lorenzo Díaz-Cruz, J. J. Toscano
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Higgs and Beyond Standard Model Searches at LEP
Extensive searches for Higgs bosons and other new phenomena predicted by extensions of the Standard Model have been performed at LEP. A summary is given reviewing the principal aspects and presenting a selection of results.Comment: 10 pages, 7 figures ...
Sguazzoni, Giacomo
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Decrypting cancer's spatial code: from single cells to tissue niches
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik+4 more
wiley +1 more source
Direct
Ken Kiers, Amarjit Soni, Guo-Hong Wu
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The 20th century brought us enormous advances in understanding the most basic constituents of space, time, and matter. All known particles and forces are assembled and described in what is known as “The Standard Model”. This allows us to calculate precisely what happens when particles collide with energies up to the equivalent of a trillion Volt for ...
openaire +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts+8 more
wiley +1 more source