Results 51 to 60 of about 3,618,801 (299)

Beyond the Standard Model

open access: yes, 1993
The standard model of particle physics is marvelously successful. However, it is obviously not a complete or final theory. I shall argue here that the structure of the standard model gives some quite concrete, compelling hints regarding what lies beyond ...
Amaldi   +7 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Statistical process control to monitor use of a web‐based autoplanning tool

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens   +5 more
wiley   +1 more source

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Treatment planning with a 2.5 MV photon beam for radiation therapy

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi   +5 more
wiley   +1 more source

Ultraviolet completion of a composite asymmetric dark matter model with a dark photon portal

open access: yesJournal of High Energy Physics, 2019
Composite asymmetric dark matter scenarios naturally explain why the dark matter mass density is comparable with the visible matter mass density. Such scenarios generically require some entropy transfer mechanism below the composite scale; otherwise ...
Masahiro Ibe   +4 more
doaj   +1 more source

Gravitational waves and dark photon dark matter from axion rotations

open access: yesJournal of High Energy Physics, 2021
An axion rotating in field space can produce dark photons in the early universe via tachyonic instability. This explosive particle production creates a background of stochastic gravitational waves that may be visible at pulsar timing arrays or other ...
Raymond T. Co   +2 more
doaj   +1 more source

Higgs: Standard Model and Beyond

open access: yes, 2002
In this talk, I will discuss possible new physics effects that modify the interaction of Higgs boson(s) with top and bottom quarks, and discuss how to detect such effects in current and future high energy colliders.Comment: LaTeX, 8 pages including 1 ...
Yuan, C. -P.
core   +2 more sources

CP Violation Beyond the Standard Model [PDF]

open access: yes, 1996
We review CP violation in various extensions of the electroweak sector of the Standard Model. A particular emphasis is put on supersymmetric models. We describe the two CP problems of supersymmetry, concerning $d_N$ and $\epsilon_K$. We critically review
Grossman, Yuval   +2 more
core   +4 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

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