Results 41 to 50 of about 27,657 (209)

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos   +9 more
wiley   +1 more source

Formulation and Evaluation of Transdermal Patches Containing BGP-15

open access: yesPharmaceutics, 2023
BGP-15 is an active ingredient with many advantages, e.g., beneficial cardiovascular and anti-inflammatory effects. The transdermal administration of BGP-15 has great potential, which has not been investigated yet, despite the fact that it is a non ...
Ildikó Bácskay   +7 more
doaj   +1 more source

BGP secure routing extension (BGP-SRx) :

open access: yes, 2021
In this paper, we first describe the problem space. Following that, we describe the design and implementation of the NIST reference implementation for RPKI-based route origin validation (BGP-OV) and BGPsec path validation (BGP-PV) within a BGP router. The system we developed is called BGP Secure Routing Extension (BGP-SRx).
Oliver Borchert   +5 more
openaire   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

open access: yesAdvanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes   +11 more
wiley   +1 more source

CSFM: A Novel Framework for Stratigraphic Forward Modeling of Clastic Systems

open access: yesGeosciences
Stratigraphic forward modeling (SFM) is a numerical approach used to reconstruct sedimentary basin evolution by simulating the infilling and tectonic evolution process of strata.
Yuangui Zhang   +5 more
doaj   +1 more source

Benford's distribution in extrasolar world: Do the exoplanets follow Benford's distribution?

open access: yes, 2016
In many real life situations, it is observed that the first digits (i.e., $1,2,\ldots,9$) of a numerical data-set, which is expressed using decimal system, do not follow a random distribution. Instead, smaller numbers are favoured by nature in accordance
Pandey, Ankit Kumar   +2 more
core   +1 more source

Expected convergence properties of BGP [PDF]

open access: yesComputer Networks, 2005
Border gateway protocol (BGP), the de facto standard used for interdomain routing, is a key enabler for interconnecting largely autonomous IP-subnetwork domains into large IP-networks. Since data transfer may not be possible until stable routes are learned, it is not only critical for BGP to converge after any policy or topology changes, but it is ...
Ramesh Viswanathan   +3 more
openaire   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Experimental Study and Theoretical Interpretation of Partial Saturation Effects on P- and S-Wave Velocities and Anisotropy in Artificial Tight Sandstones with Controlled Aligned Fractures

open access: yesApplied Sciences
This study investigates the combined effects of partial saturation and aligned fractures on P- and S-wave velocities and anisotropy in tight sandstones. Ultrasonic measurements (0.5 MHz) were conducted on three synthetic samples with a matrix porosity of
Yuangui Zhang   +5 more
doaj   +1 more source

Evolution of Matrix Gla and Bone Gla Protein Genes in Jawed Vertebrates

open access: yesFrontiers in Genetics, 2021
Matrix Gla protein (Mgp) and bone Gla protein (Bgp) are vitamin-K dependent proteins that bind calcium in their γ-carboxylated versions in mammals. They are recognized as positive (Bgp) or negative (Mgp and Bgp) regulators of biomineralization in a ...
Nicolas Leurs   +4 more
doaj   +1 more source

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