Results 21 to 30 of about 66,433 (154)

STOP 301: A Phase 3, open‐label study of safety, tolerability, and exploratory efficacy of INP104, Precision Olfactory Delivery (POD®) of dihydroergotamine mesylate, over 24/52 weeks in acute treatment of migraine attacks in adult patients

open access: yesHeadache, 2021
To report the safety, tolerability, exploratory efficacy, and patient acceptability of INP104 for the acute treatment of migraine from the Phase 3 STOP 301 trial.
T. Smith   +5 more
semanticscholar   +1 more source

Estimating price sensitivity of economic agents using discontinuity in nonlinear contracts

open access: yesQuantitative Economics, Volume 8, Issue 2, Page 397-433, July 2017., 2017
This paper proposes a method to estimate price sensitivity of economic agents exploiting discontinuity in nonlinear contracts. As an application, we study contracts between a managed care organization and hospitals for organ transplants. Exploiting donut holes in the reimbursement contracts, we show that the impact of the reimbursement rate on ...
Patrick Bajari   +3 more
wiley   +1 more source

RETRACTED ARTICLE: Inhibited MicroRNA-301 Restrains Angiogenesis and Cell Growth in Esophageal Squamous Cell Carcinoma by Elevating PTEN

open access: yesNanoscale Research Letters, 2021
Objective Esophageal squamous cell carcinoma (ESCC) is featured by early metastasis and late diagnosis. MicroRNA-301 (miR-301) is known to participate in diverse cancers. Nevertheless, effects of miR-301 on ESCC remain unexplored. Thus, we aim to explore
Bin Wang   +6 more
semanticscholar   +1 more source

Strukturbasierte Entwicklung von Protein‐Protein‐Interaktionsinhibitoren: Stabilisierung und Nachahmung von Peptidliganden

open access: yesAngewandte Chemie, Volume 127, Issue 31, Page 9022-9054, July 27, 2015., 2015
Klassenunterschiede: Inhibitoren von Protein‐Protein‐Interaktionen können durch das Nachahmen von Peptidliganden in deren bioaktiver Konformation generiert werden. Für die Entwicklung dieser Peptidmimetika steht eine Reihe von Ansätzen zur Verfügung, die in diesem Aufsatz vorgestellt werden.
Marta Pelay‐Gimeno   +3 more
wiley   +1 more source

Inhaled Levodopa (CVT-301) for the Treatment of Parkinson Disease

open access: yesNeurology Clinical Practice, 2021
Purpose of Review To investigate the efficacy and safety of CVT-301 in treating motor fluctuation in patients with Parkinson disease (PD). Recent Findings This study demonstrated that the CVT-301 group had a higher proportion of patients achieving an ON ...
Glenardi Glenardi   +3 more
semanticscholar   +1 more source

Abstract Book for the 27th Congress of the European Hematology Association

open access: yes, 2022
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley   +1 more source

Structure‐Based Design of Inhibitors of Protein–Protein Interactions: Mimicking Peptide Binding Epitopes

open access: yesAngewandte Chemie International Edition, Volume 54, Issue 31, Page 8896-8927, July 27, 2015., 2015
A matter of class: Inhibitors of protein–protein interactions can be obtained by mimicking peptide binding epitopes in their bioactive conformation. For this purpose, several strategies have been evolved to yield molecules that are generally referred to as peptidomimetics.
Marta Pelay‐Gimeno   +3 more
wiley   +1 more source

Rola uczuć w estetyce Franza Brentana [PDF]

open access: yesThe Polish Journal of Aesthetics, 2016
Tematem artykułu są uczucia w estetyce Franza Brentana. Niniejsze opracowanie dzieli się na dwie części. Pierwsza dotyczy określenia, w jaki sposób podmiot doznaje piękna.
Jakub Ruks
doaj   +1 more source

The Progenitor Age and Mass of the Black Hole Formation Candidate N6946-BH1 [PDF]

open access: yesAstrophysical Journal, 2018
The failed supernova N6946-BH1 likely formed a black hole (BH); we age-date the surrounding population and infer an age and initial mass for the progenitor of this BH formation candidate.
Jeremiah W. Murphy   +5 more
semanticscholar   +1 more source

[Retracted] Apoptosis and Molecular Targeting Therapy in Cancer

open access: yesBioMed Research International, Volume 2014, Issue 1, 2014., 2014
Apoptosis is the programmed cell death which maintains the healthy survival/death balance in metazoan cells. Defect in apoptosis can cause cancer or autoimmunity, while enhanced apoptosis may cause degenerative diseases. The apoptotic signals contribute into safeguarding the genomic integrity while defective apoptosis may promote carcinogenesis.
Mohamed Hassan   +5 more
wiley   +1 more source

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