Results 141 to 150 of about 29,657 (268)

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

Geometric and Electronic Engineering of Hydrogen Peroxide Production Electrocatalysts. [PDF]

Nanomicro Lett
Zhang C, Song M, Qi H, Hu H, Zhang L, Zhang H, Bao L, Yang H, Zhang J, Lu X.   +9 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Cerâmicos à base de SrTio3 para aplicações em dispositivos sintonizáveis

, 2005
Doutoramento em Engenharia e Ciências de MateriaisO titanato de estrôncio (ST) é conhecido como um paraeléctrico quantumno qual a permitividade dieléctrica aumenta gradualmente após arrefecimento até cerca de 0 K e nenhuma anomalia do tipo ferroeléctrica
Tkach, Oleksandr
core   +1 more source

Enantioselective synthesis of configurationally stable [5]helicenes containing 1,2-azaborine units. [PDF]

Chem Sci
Olguin C, Tabacaru C, Besse L, Simon M, Golz C, Humanes M, Fernández-Rodríguez MA, García-García P, Mücke M, Mata RA, Alcarazo M.   +10 more
europepmc   +1 more source

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Amorphous intermediates and discovery of a kinetic polymorph of BiVO₄ from heating V+Bi+Zn single-source precursors. [PDF]

Nat Commun
Hands AE, Barnes TJ, Scarperi A, Gallant BM, Vismara E, Wiktor J, Brown SE, Walker D, Menon AS, Castells-Gil J, Kubicki DJ, Pike SD.   +11 more
europepmc   +1 more source

Preparation and Thermoelectric Properties of Bi-Doped Mg₂Si_0.8Sn_0.2 Compound

MATERIALS TRANSACTIONS, 2010
Luo, Weijun, Yang, Meijun, Chen, Fei, Shen, Qiang, Jiang, Hongyi, Zhang, Lianmeng   +5 more
openaire   +1 more source

Polymorphic Superparaelectric Engineering Boosting Energy Storage Capacity in BaTiO3‐Based Ceramics

Advanced Science, EarlyView.
Herein, Ca2+ incorporation promotes the coexistence of CaTiO3‐/BaTiO3‐derived paraferroelectric states, stabilizing cubic‐orthorhombic‐tetragonal polymorphic superparaelectric phases. This minimizes polarization energy barriers, facilitating full polarization saturation without compromising efficiency.
Pan Liu, Xiang Ren, Jin Qian, Haihua Huang, Peng Li, Peng Fu, Jigong Hao, Huarong Zeng, Wei Li, Zhenxiang Cheng   +9 more
wiley   +1 more source

Growth and characterisation of thin films of CuCl and related materials

, 2012
CuCl thin films grown on (100) Si by thermal evaporation are studied by means of low temperature photoluminescence (PL) and reflectance spectroscopies. Spatially and wavelength resolved room temperature cathodoluminescence (CL) imaging of the surface of ...
Foy, Barry
core