Results 171 to 180 of about 1,134 (205)

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Stabilization of Single Metal Atoms on Graphitic Carbon Nitride: Synthetic Strategies and Emerging Applications

Advanced Science, EarlyView.
This review highlights recent advancements in stabilizing single metal atoms on graphitic carbon nitride emphasizing innovative synthesis strategies and emerging applications in electrocatalysis, photocatalysis and organic transformations, along with key challenges and future perspective. Abstract Emerging as a new frontier in catalysis science, single‐
Wenyao Zhang, Junjie Cui, Zhenjie Yao, Boyuan Zhu, Nithinraj Panangattu Dharmarajan, Ajayan Vinu, Junwu Zhu   +6 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Fuzzy Soft Ideal, Fuzzy Soft Bi-Ideal, Fuzzy Soft Quasi-Ideal and Fuzzy Soft Interior Ideal Over Ordered Γ−Semiring

Asia Pacific Journal of Mathematics, 2018
Marapureddy Murali Krishna Rao
doaj   +1 more source

Gram‐Scale Synthesis of Hafnium‐Rich Carbon Dots for Preclinical Computed Tomography Imaging Across Various Systems

Advanced Science, EarlyView.
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li, Hengrui Wu, Jianqi Deng, Qiyu Sun, Yuping Zhang, Cai Zhang, Jinbin Pan, Dingbin Liu, Xuejun Zhang, Quan Zou, Xiaoyuan Chen, Shao‐Kai Sun   +11 more
wiley   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

Advanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue, Junhao Su, Yiming Chao, Lu Liu, Xinyi Lin, Yang Xiang, Mun Kay Ho, Zezhuo Su, Junyi Chen, Zhuojuan Luo, Chengqi Lin, Ruibang Luo, Theo Aurich, Jianfeng Wu, Kelvin Sin Chi Cheung, Yuanhua Huang, Joshua W. K. Ho, Ryohichi Sugimura   +17 more
wiley   +1 more source

A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects

Advanced Science, EarlyView.
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi, Nian Liu, Jingyi Gu, Yinling Wang, Weiye Wang, Zhiwei Ke, Mingjun Xie, Wenjing Jin, Weicheng Kong, Jue Shi, Hui Pan, Yong He, Zhijian Xie   +12 more
wiley   +1 more source

vEMRec: High‐Resolution Volume Electron Microscopy Reconstruction Based on Structure‐Preserving and High‐Fidelity 3D Alignment

Advanced Science, EarlyView.
vEMRec is a frequency‐adaptive computational framework for three‐dimensional alignment in volume electron microscopy. It integrates feature‐based rigid alignment with Gaussian filter‐guided elastic registration to correct rigid misalignments and nonlinear distortions while preserving structural fidelity.
Zhenbang Zhang, Hongjia Li, Zhongjun Yang, Zhiqiang Xu, Duanchen Sun, Xin Gao, Fa Zhang, Renmin Han   +7 more
wiley   +1 more source

Boosting Photo‐Pyroelectric Effect via Tunable Polarization and Interfacial Defect Engineering

Advanced Science, EarlyView.
This study reports Ba(Ti0.85Zr0.15)O3 nanocatalysts with enhanced polarization and oxygen‐vacancy‐rich interfaces for efficient NIR‐II photo‐pyroelectric therapy. Zr doping boosts the pyroelectric coefficient and accelerates polarization switching, while oxygen vacancies improve photothermal conversion and surface reactivity.
Yanli Huang, Haifen Luo, Jie Yin, Shuai Cao, Gaolei Dong, Zhi Tan, Chunlin Zhao, Peiye Wen, Fengwei Sun, Shan Zhang, Xianzeng Zhang, Yunlu Dai, Zhen Yang, Wei Huang   +13 more
wiley   +1 more source

Nanozymes for Energy and Environmental Sustainability

Advanced Science, EarlyView.
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley   +1 more source