Application of molecular modeling to urokinase inhibitors development. [PDF]
Urokinase‐type plasminogen activator (uPA) plays an important role in the regulation of diverse physiologic and pathologic processes. Experimental research has shown that elevated uPA expression is associated with cancer progression, metastasis, and shortened survival in patients, whereas suppression of proteolytic activity of uPA leads to evident ...
Sulimov VB +9 more
europepmc +4 more sources
Abstract Absorption- and solvent-dependent fluorescence transition moments (Ma and Mf, respectively) and energies of two differently twisted 9-(dimethylanilino)phenanthrenes are determined and compared with phenanthrene properties and with quantum chemical calculations (AM1 and CNDO/S-CI) to derive the electronic and molecular structure of the first ...
Michael Maus +5 more
openaire +3 more sources
Indazole–Quinolone Hybrids as Anti-Virulence Agents against Pseudomonas aeruginosa
Antibiotic resistance is a critical public health issue. Among the multi-drug resistant microorganisms in question, Pseudomonas aeruginosa has been designated by the WHO as a priority threat.
Marie Hanot +8 more
doaj +3 more sources
Recent innovations in crop protection research. [PDF]
This review summarizes the latest innovations presented at the 15th IUPAC International Congress on Crop Protection Chemistry in New Delhi in 2023. New products and approaches to control insects, nematodes, diseases, and weeds are discussed, as well as recent advancements in crop enhancement and green pest management research.
Maienfisch P, Koerber K.
europepmc +2 more sources
Study of the antiarrhythmic activity of linear alkoxyphenylazalkanes in the model of reperfusion arrythmias in rats [PDF]
The antiarrhythmic activity of bis-alkoxyphenyltriazaalkanes 1 and bis-alkoxyphenyldiazaalkanes 2 was analyzed in a model of reperfusion arrhythmia in rats.
G. V. Mokrov +7 more
core +4 more sources
The hERG subtype potassium channel (Kv11.1) is one of the most important and one of the most studied biological targets for the creation of cardioprotective agents.
G. V. Mokrov
doaj +1 more source
Heat Treatment Condition Influence on Novokuibyshevsk Vacuum Residue Component Composition [PDF]
The article presents the information about thermal degradation of Novokuibyshevsk vacuum residue and change of products composition during this process. The optimal conditions for the thermal destruction of vacuum residue components were established. The
Golovko, A. +4 more
core +2 more sources
Composition of Initiated Cracking Products of High-sulfur Natural Bitumen [PDF]
The analysis of the cracking products of bitumen Karmalskoye deposits (the content of fractions boiling up to 200 °C 6,7% wt.) has been performed. The influence of power plant coal ash microspheres on orientation of cracking bitumen components is stated.
Dombrovskaya, A. S. +4 more
core +1 more source
Re-entrant Nematic Phase Established for Several Homologous Biaromatic Liquid Crystals by Investigation of Binary Mixed Systems [PDF]
Several homologous series of biaromatic liquid crystals with structure type CnH2n+1O • C6H4 • M•C6H4-CN are investigated. By studying the phase transition temperatures in binary mixed systems a "re-entrant" nematic phase N(re) is established for all ...
Göbl-Wunsch, A., Heppke, G., Hopf, R.
core +1 more source
A Lean Methane Prelixed Laminar Flame Doped witg Components of Diesel Fuel. Part I: n)Butylbenzene [PDF]
To better understand the chemistry involved during the combustion of components of diesel fuel, the structure of a laminar lean premixed methane flame doped with n-butylbenzene has been investigated.
Battin-Leclerc, Frédérique +3 more
core +3 more sources

