Results 151 to 160 of about 304,459 (351)

Probabilistic Lagrangian bias estimators and the cumulant bias expansion [PDF]

open access: green
Jens Stücker   +4 more
openalex   +1 more source

Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and CSF Cell Composition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich   +10 more
wiley   +1 more source

An Alternative System GMM Estimation in Dynamic Panel Models [PDF]

open access: yes
The system GMM estimator in dynamic panel data models which combines two moment conditions, i.e., for the differenced equation and for the model in levels, is known to be more efficient than the first-difference GMM estimator. However, an initial optimal
Housung Jung, Hyeog Ug Kwon
core  

A Phasor-Data-Based State Estimator Incorporating Phase Bias Correction

open access: green, 2010
Luigi Vanfretti   +3 more
openalex   +2 more sources

A New Modified Biased Estimator for Zero Inflated Poisson Regression Model

open access: green, 2023
Aamna Khan   +6 more
openalex   +1 more source

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam   +6 more
wiley   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini   +13 more
wiley   +1 more source

Higher Order Improvements for Approximate Estimators [PDF]

open access: yes
Many modern estimation methods in econometrics approximate an objective function, through simulation or discretization for instance. The resulting "approximate" estimator is often biased; and it always incurs an efficiency loss.
Bernard Salanié, Dennis Kristensen
core  

A simulation-based evidence on the improved performance of a new modified leverage adjusted heteroskedastic consistent covariance matrix estimator in the linear regression model

open access: yesKuwait Journal of Science, 2018
In this paper, we present a new heteroskedastic consistent (HC) covariance matrix estimator which considers the effect of leverage observations and which has a better approximation of its true asymptotic distribution.
Nuzhat Aftab, Sohail Chand
doaj  

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