ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
BIASES AND COVARIANCES OF MAXIMUM LIKELIHOOD ESTIMATORS
K.O. Bowman, L. R. Shenton
openalex +2 more sources
Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan +12 more
wiley +1 more source
Intercept Estimation of Semi-Parametric Joint Models in the Context of Longitudinal Data Subject to Irregular Observations. [PDF]
Ledesma L, Pullenayegum E.
europepmc +1 more source
The Variational Attitude Estimator in the Presence of Bias in Angular\n Velocity Measurements [PDF]
Maziar Izadi +4 more
openalex +1 more source
Efficiency of naive estimators for accelerated failure time models under length‐biased sampling
Pourab Roy +2 more
openalex +2 more sources
A diagnostic for bias in linear mixed model estimators induced by dependence between the random effects and the corresponding model matrix [PDF]
Andrew T. Karl, Dale L. Zimmerman
openalex +1 more source
Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting +12 more
wiley +1 more source
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source
On the mixed-model analysis of covariance in cluster-randomized trials. [PDF]
Wang B +5 more
europepmc +1 more source

