Results 81 to 90 of about 58,542 (312)
An assessment of three variance estimators for the k-nearest neighbour technique
Silva Fennica, 2013 A jackknife (JK), a bootstrap (BOOT), and an empirical difference estimator (EDE) of totals and variance were assessed in simulated sampling from three artificial but realistic complex multivariate populations (Nâ=â8000 elements) organized in ...
Magnussen, Steen
doaj +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Robust biased estimators for Poisson regression model: Simulation and applications [PDF]
, 2023 Adewale F. Lukman +2 more
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Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Generalized Exponential Type Estimator for Population Variance in Survey Sampling
Revista Colombiana de Estadística, 2014 In this paper, generalized exponential-type estimator has been proposed for estimating the population variance using mean auxiliary variable in single-phase sampling. Some special cases of the proposed generalized estimator have also been discussed.
AMBER ASGHAR +2 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Journal of Probability and Statistics, 2019 Kernel density estimators due to boundary effects are often not consistent when estimating a density near a finite endpoint of the support of the density to be estimated.
Nelson Kiprono Bii +2 more
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EXACT BIAS OF ESTIMATOR FOR UAR(1) MODEL WITH MISSING OBSERVATIONS
, 2022 Mahmoud M. Abdelwahab
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Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source