Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Black and Latinx Primary Caregiver Considerations for Developing and Implementing a Machine Learning-Based Model for Detecting Child Abuse and Neglect With Implications for Racial Bias Reduction: Qualitative Interview Study With Primary Caregivers. [PDF]
Landau AY +6 more
europepmc +1 more source
Joint models for noise annoyance and WTP for road noise reduction [PDF]
Previous CV studies of the WTP for road noise reduction have used stated annoyance as an independent variable. We argue that this may be inappropriate due to potential endogeneity bias.
Mogens Fosgerau, Thomas Bue Bjørner
core
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Integration of model-based recursive partitioning with bias reduction estimation: a case study assessing the impact of Oliver's four factors on the probability of winning a basketball game. [PDF]
Migliorati M, Manisera M, Zuccolotto P.
europepmc +1 more source
A Behavioral Confirmation and Reduction of the Natural versus Synthetic Drug Bias
Research reveals a biased preference for natural versus synthetic drugs; however, this research is based upon self-report and has not examined ways to reduce the bias. We examined these issues in five studies involving 1,125 participants.
Dillard, Amanda J. +3 more
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To Be Muslim or “Muslim-Looking” in America: A Comparative Exploration of Racial and Religious Prejudice in the 21st Century [PDF]
This Essay begins with a confession. In taking implicit association tests ( IATs ) designed to measure my unconscious attitude toward two particular demographic groups, I discovered that I, an African-American, harbored a slight automatic preference ...
Cashin, Sheryll
core +2 more sources
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Bias Reduction by Recursive Mean Adjustment in Dynamic Panel Data Models [PDF]
Accurate estimation of the dominant root of a stationary but persistent time series are required to determine the speed at which economic time series, such as real exchange rates or interest rates, adjust towards their mean values.
Chi-Young Choi +2 more
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