Results 111 to 120 of about 172,938 (287)

New robust ridge-type estimators for beta regression under multicollinearity and outliers with application to breast cancer data

Applied Mathematics in Science and Engineering
The beta regression model (BRM) is a widely applied modeling approach for data bounded within the open interval (0, 1), and it is extensively used in fields such as chemistry, environmental science, medicine, and biology.
Ali T. Hammad, I. Elbatal, Ohud A. Alqasem, Ehab M. Almetwally, Amin M. A. Haleeb, Abdirashid M. Yousuf, M. M. Abd El-Raouf, Ahmed M. Gemeay   +7 more
doaj   +1 more source

Bias Removal for Goldstein Filtering Power Using a Second Kind Statistical Coherence Estimator

Remote Sensing, 2018
The adaptive Goldstein filter driven by InSAR coherence is one of the most famous frequency domain-based filters and has been widely used to improve the quality of InSAR measurement with different noise features. However, the filtering power is biased to
Xin Tian, Mi Jiang, Ruya Xiao, Rakesh Malhotra   +3 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Estimating software reliability using size-biased modelling

Journal of Applied Statistics
Software testing is an important step in software development where inputs are administered repeatedly to detect bugs present in the software. In this paper, we have considered the estimation of total number of bugs and software reliability as a size-biased sampling problem by introducing the concept of eventual bug size as a latent variable.
Soumen Dey, Ashis Kumar Chakraborty
openaire   +3 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Generalized ratio-product-type estimator for variance using auxiliary information in simple random sampling

Kuwait Journal of Science, 2018
This paper suggests a new generalized ratio-product-type estimator for population variance of study variable utilizing information obtained from two auxiliary variables.
Muhammad Ismail, Nazia Kawnal, Muhammad Q. Shahbaz   +2 more
doaj  

Estimation Through Calibration Under Stratified Sampling with Non-Response and Measurement Error Effects

Mathematics
In survey sampling, the presence of non-response and measurement error often leads to biased and inefficient estimates, particularly in stratified random sampling designs.
Manoj K. Chaudhary, Mahmoud M. Abdelwahab, Nishtha Bhardwaj, Mustafa M. Hasaballah   +3 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source